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Adj Assoc Prof Yeo Khung Keong from National Heart Centre Singapore

Adj Assoc Prof Yeo Khung Keong

​​​​​​​​​​MBBS (S’pore), FACC, FAMS, FSCAI, ABIM (Internal Med, Cardiology & Interventional Cardiology, USA), ABVM (Vascular Medicine & Endovascular, USA)

Senior Consultant

National Heart Centre Singapore

Specialty: Cardiology

Sub-specialties: Interventional Cardiology, Structural Heart Disease, Vascular Medicine, Peripheral Arterial Interventions

Clinical Appointments

  • Senior Consultant NHCS Cardiology @ SKH Sengkang General HospitalSengkang General Hospital
  • Senior Consultant Department of Cardiology National Heart Centre SingaporeNational Heart Centre Singapore

Academic Appointments

  • Academic Vice Chair, Training & Education SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme
  • Research EXCO SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme

Profile

Adjunct Associate Professor Yeo Khung Keong is a Senior Consultant with the Department of Cardiology at the National Heart Centre Singapore. He is the Academic Vice-Chair of Training and Education, and the Research EXCO in the SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme. Adj Assoc Prof Yeo is also the Deputy Group Chief Medical Informatics Officer (Research) of SingHealth.

Adj Assoc Prof Yeo graduated in 1997 from the National University of Singapore where he obtained his Bachelor of Medicine and Surgery. He subsequently trained in the United States of America and obtained his American Board of Internal Medicine Certifications in Internal Medicine (University of Hawaii), Cardiovascular Medicine (University of California, Davis), Interventional Cardiology (University of California, Davis). He then spent an additional year training with a world-renowned cardiologist in peripheral arterial and carotid interventions. He is also Board-Certified by the American Board of Vascular Medicine in Vascular Medicine and in Endovascular procedures.

During his time at UC Davis, he trained in the MitraClip percutaneous repair of the mitral valve for mitral regurgitation. Currently, Adj Assoc Yeo leads the MitraClip programme at the National Heart Centre Singapore, the first in Asia. In Singapore, Adj Assoc Prof Yeo is the Programme Director of the Singhealth Cardiology Senior Residency Programme.

His subspecialty interests are in interventional cardiology, structural heart disease, vascular medicine and peripheral arterial interventions.​​

Education

  • SMU-SingHealth Graduate Diploma in Healthcare Management and Leadership (GDHM), Singapore Management University, 2015
  • Bachelor of Medicine and Bachelor of Surgery (M.B.B.S), National University of Singapore, 1997

Professional Appointments and Committee Memberships

  • Academic Vice Chair, Education and Training, SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme
  • Research EXCO, SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme
  • Deputy Group Chief Medical Informatics Officer (Research), SingHealth, Oct 2018 – Present
  • ​Chair, Chapter of Cardiologists, Academy of Medicine, May 2017 – Present
  • Chair, Scientific Advisory Board, Asian Pacific Society of Cardiology, 2015 – Present
  • Senior Consultant, Department of Cardiology, National Heart Centre Singapore 2013 – Present
  • Fellow, Academy of Medicine Singapore, 2013
  • Fellow, American College of Cardiology, 2012
  • Fellow, Society for Cardiovascular Angiography and Interventions, 2012
  • Member, American Heart Association, 2012
  • Ordinary Member, Singapore Cardiac Society, 2012
  • Full membership, Academic Medicine Education Institute, 10/2012​

Awards

  • ​SingHealth Excellence Awards 2016 – Outstanding Educator
  • Service Quality Silver Award, Singhealth 2013
  • Service Quality Bronze Award, NHCS 2013
  • Winner, 2008 Cardiovascular Research Award, Division of Cardiovascular Medicine, University of California, Davis, Sacramento, California
  • Best resident, Nephrology, 2005, Internal Medicine Residency Program University of Hawaii, Honolulu, Hawaii
  • Best resident, Cardiology, 2005, Internal Medicine Residency Program University of Hawaii, Honolulu, Hawaii
  • Best Internal Medicine Resident 2005, Queens Medical Center, Honolulu, Hawaii

Publications and Research Trials

  • Clinical Outcomes of Bioresorbable Scaffold in Coronary Artery Disease: A Systematic Literature Review. Keh YS, Yap J, Yeo KK, Koh TH, Eeckhout E. J Interv Cardiol. 2016 Jan 5. doi: 10.1111/joic.12260. [Epub ahead of print].
  • Correlation of the New York Heart Association Classification and the 6-Minute Walk Distance: A Systematic Review. Yap J, Lim FY, Gao F, Teo LL, Lam CS, Yeo KK. Clin Cardiol. 2015 Oct;38(10):621-8. doi: 10.1002/clc.22468. Epub 2015 Oct 7.
  • The MitraClip Asia-Pacific registry: Differences in outcomes between functional and degenerative mitral regurgitation. Tay E, Muda N, Yap J, Muller DW, Santoso T, Walters DL, Liu X, Yamen E, Jansz P, Yip J, Zambahari R, Passage J, Ding ZP, Wang J, Scalia G, Soesanto AM, Yeo KK. Catheter Cardiovasc Interv. 2015 Oct 28. doi: 10.1002/ccd.26289. [Epub ahead of print]
  • Venous Access Closure Using the Double-ProGlide Preclose Technique After MitraClip Implantation: Long-Term Clinical and Duplex Ultrasound Outcomes. Yeo KK, Yap J, Tan JW, Lim ST, Koh TH. J Invasive Cardiol. 2015 Nov 15. pii: JIC20151115-3. [Epub ahead of print]
  • Acute stent thrombosis due to stent underexpansion managed with rotational atherectomy. Devidutta S, Yeo KK. Cardiovasc Revasc Med. 2015 Nov 11. pii: S1553-8389(15)00266-3. doi: 10.1016/j.carrev.2015.10.003. [Epub ahead of print]
  • Percutaneous mitral valve repair with the mitraclip: Early results from the mitraclip asia-pacific registry (mars). Yeo KK, Yap J, Yamen E, Muda N, Tay E, Walters DL, Santoso T, Liu X, Jansz P, Yip J, Zambahari R, Passage J, Koh TH, Wang J, Scalia G, Kuntjoro I, Soesanto AM, Muller D. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 2014
  • Association between statin medications and mortality, major adverse cardiovascular event, and amputation-free survival in patients with critical limb ischemia. Westin GG, Armstrong EJ, Bang H, Yeo KK, Anderson D, Dawson DL, Pevec WC, Amsterdam EA, Laird JR. Journal of the American College of Cardiology. 2014;63:682-690
  • Endovascular recanalization of infrapopliteal occlusions in patients with critical limb ischemia. Singh GD, Armstrong EJ, Yeo KK, Singh S, Westin GG, Pevec WC, Dawson DL, Laird JR. Journal of vascular surgery. 2014
  • Angiographic characteristics of definite stent thrombosis: Role of thrombus grade, collaterals, epicardial coronary flow, and myocardial perfusion. Reeves RR, Patel M, Armstrong EJ, Sab S, Waldo SW, Yeo KK, Shunk KA, Low RI, Rogers JH, Mahmud E. Catheterization and cardiovascular interventions: official journal of the Society for Cardiac Angiography & Interventions. 2014
  • Nitinol self-expanding stents vs. Balloon angioplasty for very long femoropopliteal lesions. Armstrong EJ, Saeed H, Alvandi B, Singh S, Singh GD, Yeo KK, Anderson D, Westin GG, Dawson DL, Pevec WC, Laird JR. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 2014;21:34-43
  • Adherence to guideline-recommended therapy is associated with decreased major adverse cardiovascular events and major adverse limb events among patients with peripheral arterial disease. Armstrong EJ, Chen DC, Westin GG, Singh S, McCoach CE, Bang H, Yeo KK, Anderson D, Amsterdam EA, Laird JR. Journal of the American Heart Association. 2014;3:e000697
  • Association between statin medications and mortality, major adverse cardiovascular event, and amputation-free survival rates in patients with critical limb ischemia. Westin GG, Armstrong EJ, Bang H, Yeo KK, Anderson D, Dawson DL, Pevec WC, Amsterdam EA, Laird JR. J Am Coll Cardiol. 2013
  • Mid-term outcomes following endovascular re-intervention for iliac artery in-stent restenosis Catheter Cardiovasc Interv. Javed U, Balwanz CR, Armstrong EJ, Yeo KK, Singh GD, Singh S, Anderson D, Westin GG, Pevec WC, Laird JR. 2013 Apr 24
  • Transradial and transfemoral coronary angiography and interventions: 1-Year outcomes after initiating the transradial approach in a cardiology training program. Balwanz CR, Javed U, Singh GD, Armstrong EJ, Southard JA, Wong GB, Yeo KK, Low RI, Laird JR Jr, Rogers JH. American heart journal. Mar 2013;165(3):310-316.
  • Comparison of procedural success and long-term outcomes of stent thrombosis in coronary bypass grafts versus native coronary arteries. Waldo SW, Armstrong EJ, Yeo KK, et al. The American journal of cardiology. Mar 1 2013;111(5):689-694.
  • Gender-related variation in the clinical presentation and outcomes of critical limb ischemia. McCoach CE, Armstrong EJ, Singh S, Javed U, Anderson D, Yeo KK, Westin GG, Hedayati N, Amsterdam EA, Laird JR Jr. Vascular medicine. Feb 2013;18(1):19-26.
  • Percutaneous mitral valve repair with MitraClip for severe functional mitral regurgitation. Yeo KK, Ding ZP, Chua YL, et al. Singapore medical journal. Jan 2013;54(1):e9-e12.
  • Procedural success and long-term outcomes of aspiration thrombectomy for the treatment of stent thrombosis. Waldo SW, Armstrong EJ, Yeo KK, Patel M, Reeves R, Macgregor JS, Low RI, Mahmud E, Rogers JH, Shunk K. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2013
  • Angiographic characteristics of femoropopliteal in-stent restenosis: Association with long-term outcomes after endovascular intervention. Armstrong EJ, Singh S, Singh GD, Yeo KK, Ludder S, Westin G, Anderson D, Dawson DL, Pevec WC, Laird JR. Catheterization and cardiovascular interventions: official journal of the Society for Cardiac Angiography & Interventions. 2013
  • Excimer laser with adjunctive balloon angioplasty and heparin-coated self-expanding stent grafts for the treatment of femoropopliteal artery in-stent restenosis: twelve-month results from the SALVAGE study. Laird JR, Jr., Yeo KK, Rocha-Singh K, et al. Catheter Cardiovasc Interv. Nov 1 2012;80(5):852-859.
  • Right pace, wrong place. Ann Acad Med Singapore. Lim CP, Yeo KK, Tan BY, Liew R, Tan JW. Sep 2012;41(9):417-419.
  • Coronary artery bypass operations for elderly patients in California, 2003 to 2008. Li Z, Amsterdam EA, Yeo KK, et al. Ann Thorac Surg. Apr 2012;93(4):1167-1172.
  • Angiographically confirmed stent thrombosis in contemporary practice: Insights from intravascular ultrasound. Armstrong EJ, Kwa AT, Yeo KK, et al. Catheter Cardiovasc Interv. Apr 18 2012.
  • Contemporary clinical characteristics, treatment, and outcomes of angiographically confirmed coronary stent thrombosis: results from a multicenter California registry. Yeo KK, Mahmud E, Armstrong EJ, et al. Catheter Cardiovasc Interv. Mar 1 2012;79(4):550-556.
  • Comparison of clinical characteristics, treatments and outcomes of patients with ST-elevation acute myocardial infarction with versus without new or presumed new left bundle branch block (from NCDR(R)). Yeo KK, Li S, Amsterdam EA, et al. The American journal of cardiology. Feb 15 2012;109(4):497-501.
  • AsiaPCR/SingLive: in its third year and growing. Lim E, Lim CP, Muller O, Yeo KK, Lim ST, Koh TH, Eechkout E. EuroIntervention. Feb 2012;7(10):1144-1146.
  • Clinical presentation, management, and outcomes of angiographically documented early, late, and very late stent thrombosis. Armstrong EJ, Feldman DN, Wang TY, Kaltenbach LA, Yeo KK, Wong SC, Spertus J, Shaw RE, Minutello RM, Moussa I, Ho KK, Rogers JH, Shunk KA. JACC Cardiovasc Interv. Feb 2012;5(2):131-140.
  • The treatment of femoropopliteal in-stent restenosis: back to the future. Laird JR, Yeo KK. J Am Coll Cardiol. Jan 3 2012;59(1):24-25.
  • Angiographic stent thrombosis at coronary bifurcations: short- and long-term prognosis. Armstrong EJ, Yeo KK, Javed U, et al. JACC Cardiovasc Interv. Jan 2012;5(1):57-63.
  • Outcomes following treatment of femoropopliteal in-stent restenosis: A single center experience. Yeo KK, Malik U, Laird JR. Catheterization and cardiovascular interventions: official journal of the Society for Cardiac Angiography & Interventions. May 12 2011.
  • Early duplex scanning after infrainguinal endovascular therapy. Humphries MD, Pevec WC, Laird JR, Yeo KK, Hedayati N, Dawson DL. J Vasc Surg. Feb 2011;53(2):353-358.
  • Relation of race, ethnicity and cardiac surgeons to operative mortality rates in primary coronary artery bypass grafting in California. Castellanos LR, Li Z, Yeo KK, Young JN, Ayanian JZ, Amsterdam EA. The American journal of cardiology. Jan 2011;107(1):1-5.
  • Life-threatening coronary sinus thrombosis following catheter ablation: case report and review of literature. Yeo KK, Davenport J, Raff G, Laird JR. Cardiovasc Revasc Med. Oct-Dec 2010;11(4):262 e261-265.
  • Early duplex scanning after infrainguinal endovascular therapy. Humphries MD, Pevec WC, Laird JR, Yeo KK, Hedayati N, Dawson DL. J Vasc Surg. Oct 23 2010.
  • Off-pump bypass surgery and postoperative stroke: California coronary bypass outcomes reporting program. Li Z, Denton T, Yeo KK, et al. Ann Thorac Surg. Sep 2010;90(3):753-759.
  • The role of stent-grafts for prevention and treatment of restenosis. Kwa AT, Yeo KK, Laird JR. J Cardiovasc Surg (Torino). Aug 2010;51(4):579-589.
  • Operative mortality in women and men undergoing coronary artery bypass grafting (from the California Coronary Artery Bypass Grafting Outcomes Reporting Program). Bukkapatnam RN, Yeo KK, Li Z, Amsterdam EA. The American journal of cardiology. Feb 1 2010;105(3):339-342.
  • Recovery of methamphetamine associated cardiomyopathy predicted by late gadolinium enhanced cardiovascular magnetic resonance. Lopez JE, Yeo KK, Caputo G, Buonocore M, Schaefer S. J Cardiovasc Magn Reson. 2009;11:46.
  • Late surgical mitral valve repair after percutaneous repair with the MitraClip system. Rogers JH, Yeo KK, Carroll JD, et al. J Card Surg. Nov-Dec 2009;24(6):677-681.
  • The effect of posture on Cheyne-Stokes respirations and hemodynamics in patients with heart failure. Soll BA, Yeo KK, Davis JW, Seto TB, Schatz IJ, Shen EN. Sleep. Nov 2009;32(11):1499-1506.
  • A comparison of echocardiographic findings in young adults with cardiomyopathy: with and without a history of methamphetamine abuse. Ito H, Yeo KK, Wijetunga M, Seto TB, Tay K, Schatz IJ. Clin Cardiol. Jun 2009;32(6):E18-22.
  • Off-pump coronary artery bypass graft surgery in California, 2003 to 2005. Li Z, Yeo KK, Parker JP, Mahendra G, Young JN, Amsterdam EA. American heart journal. Dec 2008;156(6):1095-1102
  • Percutaneous treatment of a large superior mesenteric artery pseudoaneurysm and arteriovenous fistula: a case report. Yeo KK, Dawson DL, Brooks JL, Laird JR. J Vasc Surg. Sep 2008;48(3):730-734.
  • Direct flow medical percutaneous aortic valve: proof of concept. Low RI, Bolling SF, Yeo KK, Ebner A. EuroIntervention. Aug 2008;4(2):256-261.
  • Food and Drug Administration-approved endovascular repair devices for abdominal aortic aneurysms: a review. Tan JW, Yeo KK, Laird JR. J Vasc Interv Radiol. Jun 2008;19(6 Suppl):S9-S17.
  • Excimer laser assisted angioplasty for complex infrainguinal peripheral artery disease: a 2008 update. Tan JW, Yeo KK, Laird JR. J Cardiovasc Surg (Torino). Jun 2008;49(3):329-340.
  • Severity of chronic kidney disease as a risk factor for operative mortality in nonemergent patients in the California coronary artery bypass graft surgery outcomes reporting program. Yeo KK, Li Z, Yeun JY, Amsterdam E. The American journal of cardiology. May 1 2008;101(9):1269-1274.
  • Use of stent grafts and coils in vessel rupture and perforation. Yeo KK, Rogers JH, Laird JR. J Interv Cardiol. Feb 2008;21(1):86-99.
  • Aortic stenosis: assessment of the patient at risk. Yeo KK, Low RI. J Interv Cardiol. Dec 2007;20(6):509-516.
  • Dual mechanism platypnea-orthodeoxia syndrome from severe right coronary artery stenosis and a patent foramen ovale. Yeo KK, Rogers JH. Catheter Cardiovasc Interv. Sep 2007;70(3):440-444.
  • Clinical characteristics and 30-day mortality among Caucasians, Hispanics, Asians, And African-Americans in the 2003 California coronary artery bypass graft surgery outcomes reporting program. Yeo KK, Li Z, Amsterdam E. The American journal of cardiology. Jul 1 2007;100(1):59-63.
  • The association of methamphetamine use and cardiomyopathy in young patients. Yeo KK, Wijetunga M, Ito H, et al. Am J Med. Feb 2007;120(2):165-171.
  • Ethnicity modifies the association between diabetes mellitus and ischaemic heart disease in Chinese, Malays and Asian Indians living in Singapore. Yeo KK, Tai BC, Heng D, et al. Diabetologia. Dec 2006;49(12):2866-2873.
  • Valve replacement in endocarditis: setting limits in noncompliant intravenous drug abusers. Yeo KK, Chang WJ, Lau JM, Tan SY. Hawaii Med J. Jun 2006;65(6):168, 170-161.
  • Tachycardia-induced elevations in cardiac troponin in the absence of coronary artery disease. Yeo KK, Cruz L, Hong R. Hawaii Med J. Mar 2006;65(3):86-87.
  • Procedural success and complications following percutaneous coronary interventions among Asians and Pacific Islanders. Yeo KK, Beauvallet S, Mau MK, Seto TB. Clin Cardiol. Sep 2005;28(9):429-432.
  • Multiple cardiac papillary fibroelastoma and transient left ventricular apical ballooning syndrome in an elderly woman: case report. Yeo KK, Fukuyama O. J Heart Valve Dis. Jan 2005;14(1):137-139.
  • Stereotactic brain biopsies in AIDS patients--early local experience. Yeo KK, Yeo TT, Chan CY, Sitoh YY, Teo J, Wong SY. Singapore medical journal. Apr 2000;41(4):161-166.

Research Trials

  • The role of aspirin and thienopyrdine non-responsiveness in peripheral arterial disease, PI 
  • 3-Dimensional Reconstruction and Quantitation of the Mitral Valve by Echocardiography for Assessment of Short and Long Term Consequences of Percutaneous Repair of Mitral Regurgitation, PI
  • Long-term clinical outcomes, cost-of-care, quality-of-care and re-admission rates in patients with coronary artery disease or congestive heart failure in Singapore (SingCLOUD): Proof of Concept, PI
  • Empathy in SingHealth Residents, PI, 31 Mar 2015 – 31 Mar 2017 (2 years)
  • A portable video-based patient education tool for cardiac catheterisation, PI, 1 Oct 2015 – 30 Sep 2017 (2 year)
  • SingHEART: A long-term longitudinal study on the cardiovascular health of normal people with biobanking, deep phenotyping, cardiac MRI and physical activity, PI, 1 Jun 2015 – 1 Jun 2016 (1 year)