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Dr Cai Xinzhe James

Dr Cai Xinzhe James

MBBS, MRCP (UK), M Med (Int Med)​


National Heart Centre Singapore

Specialty: Cardiology

Clinical Interest: Echocardiography, Nuclear Medicine

Clinical Appointments

  • Consultant Department of Cardiology National Heart Centre SingaporeNational Heart Centre Singapore


Dr Cai Xinzhe James is a Consultant from the Department of Cardiology at National Heart Centre Singapore.

His subspecialty interest is in non-invasive cardiac imaging, specifically Echocardiography and Nuclear Cardiology. He has a special interest in the use of risk prediction models in the evaluation of patients with chest pain and the utility of stress testing in these patients.


  • ​Specialist Accreditation in Cardiology, February 2022
  • Masters of Medicine (Internal Medicine), June 2016
  • Membership of the Royal College of Physicians, United Kingdom, May 2016
  • Bachelor of Medicine and Bachelor of Surgery (MBBS), National University of Singapore, April 2013

Professional Appointments and Committee Memberships

  • Consultant, Department of Cardiology, National Heart Centre Singapore, May 2024 – Present
  • Associate Consultant, Department of Cardiology, National Heart Centre Singapore, March 2022 – April 2024
  • Clinical Instructor, Duke-NUS Medical School, 17 August 2022- Present
  • Clinical Educator, Lee Kong Chian School of Medicine, July 2021 – Present
  • Singhealth Associate in Education, SingHealth, September 2020 – Present
  • Organizer, SGH PACES Course 2018, Singapore General Hospital, July 2017 – June 2018
  • Organizer, CADENCE and CADENCE+ Programme, SingHealth, July 2017 – June 2018


  • Outstanding Residency Award (Internal Medicine), Singhealth Residency 2018
  • Best Abstract (2nd prize), SingLIVE, 2018
  • Merchant Medal and Prize in Geriatric Medicine, National University of Singapore, 2013

Research Interests


  • Impact of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on in-hospital mortality in COVID-19 patients: a systematic review and meta-analysis, Cai XJ, Tay JCK, Kui SL, Aung ST, Tan VH, Singapore Medical J, 2021 Nov;62(11):563-567
  • Age and diabetes mellitus associated with worse outcomes after PCI in a multi-ethnic Asian dialysis patient population, Fam JM, Khoo CY, Lau YH, Weng KL, Cai XJ, Choong LHL, Allen J, Yeo KK, Singapore Medical J, 2021 Jun;62(6):300-304
  • "Catch Me If You Can": Recurrent ST-Segment Elevation Myocardial Infarction Due to Aortic Thrombus, Cai XJ, Tan TN, Chai SC, Liew CJY, Liew BWM, Lim BY, JACC Case Rep. 2020 Oct 21;2(12):1974-1978
  • Catheter ablation for atrial fibrillation in a low-volume center using contemporary technology, Tay JCK, Cai XJ, Lin J, Liang S, Him AL, Hamid SBS, Wong KCK, Yeo C, Tan VH, Int J Cardiol Heart Vasc. 2020 Oct 23;31:100661
  • Elderly Asian Patients Have Lower Revascularisation Rates and Poorer Outcomes for ST-Elevation Myocardial Infarction Compared to Younger Patients, Cai XJ, Yap J, Gao F, Koh TH, Tong KL, Ong HY, Pipin K, Tan HC, Ong MEH, Foo D, Ee B, Low LP , Chui P, Yeo KK, Ann Acad Med Singap. 2020 Jan;49(1):3-14

Research Trials