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Drug Class: Commonly Known As: Category:
Anticonvulsant ZARONTIN Adult, Children

Ethosuximide - Side Effects, Precautions, and Contraindications

What side effects can Ethosuximide cause?

Generally, the common side effects tend to occur at the beginning of treatment. Such side effects may include:

  • Mild nausea, vomiting, indigestion, abdominal pain, diarrhea and loss of appetite.
    • If the medicine upsets the stomach, take it with food or milk.
  • Drowsiness, headache, dizziness, hiccups, behavioural changes (e.g. irritability, mood change, aggressiveness)
    • Be careful when taking (or giving your child) any over-the-counter medicines. Medicines for allergy or cold symptoms can add on to the drowsiness. Be sure to supervise your child if he/she is involved in activities such as cycling or swimming.
  • Poor muscle coordination

Inform your doctor if any of the above side effects lasts more than a few days or become severe and bothersome.


Rare but serious side effects may manifest as the following symptoms. Contact your doctor as soon as possible, if you notice any of the following:

  • Skin rash
  • Any unusual bleeding or bruises, prolonged fever, sore throat, mouth sores
  • Rash, joint swelling, swelling at neck and armpits
  • Worsening or unusual behavioural changes

Inform your doctor if you notice any other unusual symptoms. Always discuss with your doctor or pharmacist if you (or your child) have any problems or difficulties during or after taking Ethosuximide.

Before taking Ethosuximide , what precautions must I follow?

What food or medicine must I avoid when I take Ethosuximide ?

Check with your doctor or pharmacist if you want to take (or give your child) any other medicines, supplements or herbal products.

  • Updated on Wednesday, September 27, 2017
  • Article contributed by Pharmacy Department KK Women's and Children's Hospital

The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth


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