Skip Ribbon Commands
Skip to main content


Drug Class: Commonly Known As: Category:
Anticonvulsant ZARONTIN Adult, Children

Ethosuximide - What is it for

Ethosuximide is used to control seizures and other problems related to the nervous system.

Ethosuximide - Side Effects, Precautions, and Contraindications

What side effects can Ethosuximide cause?

Generally, the common side effects tend to occur at the beginning of treatment. Such side effects may include:

  • Mild nausea, vomiting, indigestion, abdominal pain, diarrhea and loss of appetite.
    • If the medicine upsets the stomach, take it with food or milk.
  • Drowsiness, headache, dizziness, hiccups, behavioural changes (e.g. irritability, mood change, aggressiveness)
    • Be careful when taking (or giving your child) any over-the-counter medicines. Medicines for allergy or cold symptoms can add on to the drowsiness. Be sure to supervise your child if he/she is involved in activities such as cycling or swimming.
  • Poor muscle coordination

Inform your doctor if any of the above side effects lasts more than a few days or become severe and bothersome.


Rare but serious side effects may manifest as the following symptoms. Contact your doctor as soon as possible, if you notice any of the following:

  • Skin rash
  • Any unusual bleeding or bruises, prolonged fever, sore throat, mouth sores
  • Rash, joint swelling, swelling at neck and armpits
  • Worsening or unusual behavioural changes

Inform your doctor if you notice any other unusual symptoms. Always discuss with your doctor or pharmacist if you (or your child) have any problems or difficulties during or after taking Ethosuximide.

Before taking Ethosuximide , what precautions must I follow?

What food or medicine must I avoid when I take Ethosuximide ?

Check with your doctor or pharmacist if you want to take (or give your child) any other medicines, supplements or herbal products.

Ethosuximide - Dosage and How to Use

How should Ethosuximide be used?

Ethosuximide is usually taken 1 to 2 times a day. The doctor may start you (or your child) on a low dose and then slowly increase the dose. Follow the instructions on the label carefully and ask your pharmacist or doctor if you are unsure.

Do not take (or give) this medication more often than directed and do not stop unless instructed by your doctor. Stopping this medicine too rapidly can increase the risk of seizures or fits.

Do not change brands or dosage forms without informing your doctor.

Ethosuximide can be taken with or without food.

Oral liquid form

  • Shake well before using. Use a medicine spoon or the graduated syringe provided to measure your medicine. Do not use household spoons as they may not be accurate.

Capsule form

  • Swallow the capsule whole with a glass of water.

What should I do if I miss a dose?

Take (or give your child) the missed dose as soon as you remember and then continue to take (or give) it as you normally would. However, if it is almost time for the next dose, skip the dose you (or your child) missed and take (or give) the next dose at the usual time.

Do not double or increase the dose.          

If you (or your child) have missed more than two doses or you are not sure of what to do, consult your doctor or pharmacist.

If you (or your child) have less than two weeks supply of medication, please ensure that you have made an appointment with your neurologist or made arrangements to collect more medication.

What should I do if I overdose?

Ethosuximide - Handling

How should I handle Ethosuximide safely?

Ethosuximide - Storage

How should I store Ethosuximide ?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Ethosuximide safely?

Ethosuximide - Additional Information

If you (or your child) sees another doctor, inform him/her that you (or your child) is taking Ethosuximide before your doctor prescribes any other medications.

  • Updated on Wednesday, September 27, 2017
  • Article contributed by Pharmacy Department KK Women's and Children's Hospital

The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth


Find Your Medicines