Dr Leung Jason Hongting

​Dr. Jason Leung is a Consultant from the Department of Cardiothoracic Surgery at National Heart Centre Singapore. He graduated with departmental distinction from Duke University (USA) with a Bachelor of Science in Engineering degree, and completed his Doctor of Medicine degree at Duke-NUS Medical School in Singapore. He trained in cardiothoracic surgery under the SingHealth Cardiothoracic Surgery Clinician Scientist Residency Program. He treats patients with cardiac and thoracic disorders. 

Aside from clinical and surgical work, he has also studied the topic of chronic graft rejection following lung transplantation while at Duke University, and his research is published in peer-reviewed journals. He received the Pratt Fellowship (Duke University), National Institutes Cancer Research Training Award (Bethesda, USA) and MOHH Clinician Scientist Residency Seed Funding (Singapore) and completed a Masters of Clinical Investigation at the National University of Singapore.

• ​Cancer Research Training Award, National Institutes of Health, USA (2006)
• Pratt Research Fellow, Duke University, USA (2005-2006) 
  

• ​Lung Cancer
• Lung Transplantation
  
• Biomarkers
• Cardiac Surgery
• Thoracic Surgery
  

• ​IL-11 and non-small cell lung cancer: clinical associations and transcriptome analysis. Role as Principle investigator, supported by the Ministry of Health Clinician Scientist Residency Seed Funding (MOH-CSSDFD19OCT-0002)
• A pilot feasibility study of detection of IL-11 and other cytokines in the exhaled breath condensate (EBC) and blood of healthy volunteers. Role as Co-investigator.
  

• ​Use of Midodrine for Treatment of Chylopericardium Following Coronary Artery Bypass Grafting. Chong C, Lizwan M, Leung JH, Chao VTT, Soo IX. JTCVS Techniques (2022) doi: https://doi.org/10.1016/j.xjtc.2022.08.006
• Interleukin-11: A Potential Biomarker and Molecular Therapeutic Target in Non-Small Cell Lung Cancer. Jason Hongting Leung, Benjamin Ng, Wei-Wen Lim. Cells. 2022 Jul 21;11(14):2257.
• Gastric Malignancy Causing E. Coli Infection of a Frozen Elephant Trunk Stent Graft and the use of Transthoracic Composite muscle Flaps for Graft Salvage. Hui Chai Fong, Victor Tar Toong Chao, Jason Hongting Leung and Bien-Keem Tan. J Cardiothorac Surg Ther. 2021 July; 5(1):95-97
• Pulmonary mucormycosis with diaphragm and liver involvement in a patient with haematopoietic stem cell transplant. Jason Hongting Leung, Khong-Yik Chew, Alexander Yaw-Fui Chung, Tina Puay Theng Koh. Interact Cardiovasc Thorac Surg. 2020 Jan 1;30(1):144-145.
• Clearance of bile and trypsin in rat lungs following aspiration of human gastric fluid. Jason H Leung, Jui-Chih Chang, Emily Foltz, Sadé M Bell, Cinthia Pi, Sassan Azad, Mary Lou Everett, Zoie E Holzknecht, Nathan L Sanders, William Parker, R Duane Davis, Shaf Keshavjee, Shu S Lin. Exp Lung Res. 2016;42(1):37-43.
• The role of soluble and insoluble gastric fluid components in the pathogenesis of obliterative bronchiolitis in rat lung allografts. Jason H Leung, Jui-Chih Chang, Sadé M Bell, Zoie E Holzknecht, Samantha M Thomas, Mary Lou Everett, William Parker, R Duane Davis, Shu S Lin. Transpl Int. 2016 Feb;29(2):253-61
• Cromolyn ameliorates acute and chronic injury in a rat lung transplant model. Jui-Chih Chang, Jason Leung, Tao Tang, Zoie E Holzknecht, Matthew G Hartwig, R Duane Davis, William Parker, Soman N Abraham, Shu S Lin. J Heart Lung Transplant. 2014 Jul;33(7):749-57.
• In the face of chronic aspiration, prolonged ischemic time exacerbates obliterative bronchiolitis in rat pulmonary allografts. J-C Chang, J H Leung, T Tang, M G Hartwig, Z E Holzknecht, W Parker, R D Davis, S S Lin. Am J Transplant. 2012 Nov;12(11):2930-7.
• Chronic aspiration shifts the immune response from adaptive immunity to innate immunity in a murine model of asthma. Kuei-Ying Su, Anitra D Thomas, Jui-Chih Chang, Jason H Leung, Sean M Lee, Zoie E Holzknecht, Mary Lou Everett, W Michael Foster, Monica Kraft, William Parker, R Duane Davis, Shu S Lin. Inflamm Res. 2012 Aug;61(8):863-73.
• Gastroesophageal reflux-associated aspiration alters the immune response in asthma. Anitra D Thomas, Kuei-Ying Su, Jui-Chih Chang, Jason H Leung, Sean M Lee, Zoie E Holzknecht, Mary Lou Everett, William Parker, R Duane Davis, Shu S Lin. Surg Endosc. 2010 May;24(5):1066-74.