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Adj Asst Prof Ruan Wen

​M.D. (China), MRCP (UK), MMed (Int Med) (S'pore), FASE (USA)

Senior Consultant

National Heart Centre Singapore National Heart Centre Singapore

Specialty: Cardiology

Conditions Treated By This Doctor

Clinical Interests

Echocardiography, Pulmonary Hypertension

Clinical Appointments

Senior Consultant

Cardiology

Academic Appointments

Clinical Adjunct Assistant Professor, Duke-NUS School of Medicine

Cardiovascular Sciences Academic Clinical Programme

Clinical Assistant Professor, Yong Loo Lin School of Medicine, National University of Singapore

Clinical Educator, Lee Kong Chien School of Medicine

About Doctor

Clinical Assistant Professor Ruan Wen is a Senior Consultant in the Department of Cardiology at the National Heart Centre Singapore. She earned her Master of Medicine in Internal Medicine and is a Member of the Royal Colleges of Physicians (MRCP). She further honed her expertise during a clinical fellowship in pulmonary hypertension at the Royal Papworth Hospital in the United Kingdom. 

Her clinical practice centres on echocardiography and the comprehensive management of pulmonary hypertension, including chronic thromboembolic pulmonary hypertension (CTEPH). She leads a multidisciplinary pulmonary hypertension clinic, where she oversees a diverse range of pulmonary vascular conditions and administers advanced therapies, including home-based parenteral prostacyclin infusions for eligible patients. 

Beyond patient care, she is actively involved in medical education. She serves as Co-Course Director of the Pulmonary Hypertension Preceptorship at the National Heart Centre Singapore and is a faculty member of the SingHealth Cardiology Residency Program. Her research interests are pulmonary vascular disease and cardiovascular imaging.

Languages Spoken

  • English
  • Chinese

Education and Training

  • Royal College of Physicians (UK) Diploma, 2012
  • Master of Medicine (Internal Medicine), National University of Singapore, 2012
  • Cardiology Specialist Accreditation, Singapore, 2012
  • Doctor of Medicine, Fudan University, 1998

Professional Appointments and Committee Memberships

  • Senior Consultant, Department of Cardiology, National Heart Centre Singapore, Nov 2023 – Present
  • Consultant, Department of Cardiology, National Heart Centre Singapore, Nov 2018 – Nov 2023
  • Fellow of American Society of Echocardiography, June 2020- present
  • Faculty member, Cardiology Senior Residency Program, SingHealth Residency Nov 2017 -present
  • Member, Singapore Cardiac Society

Awards

  • ​COVID-19 Resilience Medal, Nov 2023
  • Singapore Health Long service award, 2019
  • Health manpower development Plan (HMDP) 2018
  • National Heart Center Productivity Award 2017, 2018
  • SingHealth Service Quality Award, 2016

Research Trials/Clinical Trials

Principal or Co-investigator for several trials

  • UNISUS
  • ADVANCE
  • PROSERA
  • LIGHTRAY

Publications

  • Development of a Noninvasive Prediction Score for Post-Capillary Pulmonary Hypertension in a Multi-Ethnic Asian Population.  Jiang H, Loh S, Chia SY, Ruan W, Hong JS, Ismail AB, Lim CL, Koh M, Sewa DW, Phua GC, Oh YZ, Ng SA, Hong C, Low A, Seow M, Lim ST, Tan JL, Yap J. JACC Asia. 2026 May;6(5):736-745. 
  • Performance of Risk-Stratification Scores for Patients With Pulmonary Arterial Hypertension in a Multi-Ethnic Asian Population. Jiang H, Tan JL, Ruan W, Hon JS, Ismail A, Lim CL, Perumal S, Koh M, Sewa DW, Phua GC, Oh YZ, Ng SA, Hong C, Low A, Lim ST, Yap J.Pulm Circ. 2024 Dec 29;15(1):e70032
  • Intravenous epoprostenol therapy in the treatment of pulmonary arterial hypertension in Singapore. Choo J, Yap J, Ismail A, Hon JS, Ruan W, Low A, Lim ST, Tan JL. Ann Acad Med Singap. 2024 Oct 9;53(10):627-631
  • ​Outcomes of selexipag for treatment of pulmonary arterial hypertension in an Asian population. Loo G, Yap J, Hon JS, Ismail A, Ruan W, Low A, Lim ST, Tan JL. Ann Acad Med Singap 2023;52:219-21
  • Pulmonary endarterectomy and balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension: The Singapore experience. Ruan W, Yap J, Quah K, Cheah FK, Phua GC, Sewa DW, Ismail AB, Chia A, Jenkins D, Tan JL, Chao V, Lim ST. Ann Acad Med Singap 2021;50:270-3
  • Updates on the Diagnosis and Management of Chronic Thromboembolic Pulmonary Hypertension. Ruan W, Yap JJ, Quah KK, Cheah FK, Phua GC, Sewa DW, Ismail AB, Chia AX, Jenkins D, Tan JL, Chao VT, Lim ST.Clinical.Ann Acad Med Singapore. 2020 May;49(5):320-330.
  • Mortality and hospitalization outcomes of interstitial lung disease and pulmonary hypertension in the Singapore systemic sclerosis cohort. Noviani M, Saffari SE, Tan JL, Yip JWL, Teng GG, Law WG, Chan GYL, Santosa A, Lim AYN, Hong C, Ng SA, Tay ELW, Ruan W, Yap J, Low AHL. Semin Arthritis Rheum. 2019 Nov 13.
  • Is subdural hemorrhage after pulmonary endarterectomy underrecognized? Yap J, Ruan W, Chia A, Loh K, Cheah FK, Leen Ang A, Phua GC, Sewa DW, Jenkins D, Le Tan J, Chao V, Lim ST.J Thorac Cardiovasc Surg. 2018 Jul 3. pii: S0022-5223(18)31763-X