Assoc Prof Koh Su-Mei Angela

Associate Prof Angela Koh is a Senior Consultant with the Department of Cardiology and Director of the Cardiovascular Ageing & Longevity Programme (CRANE) at the National Heart Centre Singapore. She is a nationally funded clinician-scientist in cardiovascular ageing and longevity who directs a clinical, academic and research program that seeks to enhance cardiovascular health in ageing through integration of cardiovascular imaging, biological phenotyping, technological innovations and real-world interventions.

• Director, Cardiovascular Ageing & Longevity Programme, May 2025 - Present
• Senior Consultant, Department of Cardiology, National Heart Centre Singapore, May 2019 to Present
• Associate Professor, Duke-NUS Medical School – Present
• American College of Cardiology Geriatric Cardiology Section Leadership Council, 2025
• World Heart Federation World Heart Observatory Expert Group, 2023
• Fellow, American College of Cardiology
• Fellow, Royal College of Physicians, London, UK
• Fellow, European Society of Cardiology
• Fellow, American Heart Association
• Fellow, American Society of Nuclear Cardiology
• Clinical Lecturer, Clinical Faculty Scheme, National University of Singapore, Yong Loo Lin School of Medicine, Singapore
• Clinical Teacher, Lee Kong Chian School of Medicine
• Member, Singapore Medical Association
• Member, Singapore Cardiac Society

• Distinguished Researcher Award, Singhealth Excellence Awards, 2026
• Outstanding Mentor Award, Singapore Medical Association, Wong Hock Boon Research Society, NUS, 2024
• Paul Dudley White International Scholar Award, American Heart Association, 2023
• World Heart Federation Salim Yusuf Emerging Leaders Programme, 2022
  
• Clinician Scientist Award (Investigator), National Medical Research Council, Singapore, 2022
  
• Paul Dudley White International Scholar Award, American Heart Association, 2021
  
• Clinician Scientist Award (Investigator), National Medical Research Council, Singapore, 2019
• Outstanding Mentor Award, Wong Hock Boon Society, NUS, 2017
• Singapore Health Service Quality Award 2016 (Silver)
• Singapore Health Service Quality Award and 2017 (Gold)
• Transition Award, National Medical Research Council, Singapore, 2014
• SingHealth Publish Award (Medical Research), SingHealth Foundation, 2012
• First runner-up, Young Investigator Award, at ICNC10 - Nuclear Cardiology and Cardiac CT, Amsterdam – Netherlands, 2011 
• Singapore Health Manpower Development Plan (HMDP) Fellowship, Singapore Health Services, 2011
• American Heart Association Women in Cardiology Trainee Award for Excellence, Scientific Sessions in Chicago, Illinois, 2010 
• NHCS Productivity Award, 2010 
• NHCS Productivity Award, 2009 
• Young Investigator Competition, Certificate of Merit, 14th Annual American Society of Nuclear Cardiology Scientific Session, Minneapolis, Minnesota, United States of America, 2009 
• Seah Cheng Siang M.Med (Internal M
  edicine) Gold Medal Award, National University of Singapore, 2007 

(as Principal Investigator)

• INDEPENDENCY: Tackling Disruptions to Frailty Interventions: Developing Personalized Interventions Targeted for Older Persons with Cardiac Frailty 
• ESCAP-AGE: A Multi-Centre Randomized Clinical Trial of Exercise to Retard Cardiovascular Ageing
  
• INTELLIGRATE: Intelligent Integrative Tool for Tackling Risks of Ageing-Related Cardiovascular Disease
  
• NUCLEuS: Evaluating Dynamic Myocardial Blood Flow Quantitation As a Cost Effective Care Model for Diabetic Patients with Coronary Artery Disease: A Randomized Controlled Trial
• Cardiac Ageing Study
  
• TO-ChERIsH: Trajectory of Cardiovascular Ageing, Its Determinants and Impact on Health
• CONGLOMERATE: Conglomerating the Effects of Physical Activity on Cardiovascular Longevity in Ageing 
• GLORIA - AF: Global Registry on Long-Term Oral Anti-thrombotic TReatment in PAtients with Atrial Fibrillation (Site-PI)
  
• EaRneST: Exercise and CiRculating MetabolomicS: A Pilot Randomized Controlled Trial
  

1. Tan GHM, Yang E, Tan BZY, Naghshbandi H, Loh J, Zhong X, Liu J, Lim DJ, Gao F, Kovalik J-P, Tan R-S, Yeo SY, Koh AS. A Machine Learning Approach to Conglomerate Multi-Domain Features of Cardiac Aging. European Heart Journal - Digital Health. 2026.
2. Jiang H, Wong JJ, Li L-J, Gao F, Wykrzykowska JJ, Ho KW, Takahashi S, Lee KS, Kong WKF, Poh KK, Tan R-S, Koh AS. Clinical outcomes following invasive cardiovascular interventions in frail populations: a systematic review and meta-analysis. European Heart Journal - Quality of Care and Clinical Outcomes. 2026;12(1):95-104. 
3. Jiang H, Lim DJ, Khoo CY, Cuddy SAM, Wong R, Tan R-S, Gao F, Chen Y, Dorbala S, Koh AS. Frailty status, clinical and functional outcomes in cardiac amyloidosis: a systematic review and meta-analysis. eClinicalMedicine. 2026;98.
4. Zhao X, Leng S, Tan R-S, Gao F, Teo L, Chai P, Wee HN, Chua KV, Ching J, Han S, Lee PT, Yip JW, Tan JL, Kovalik J-P, Koh AS, Zhong L. Associations Between Right Ventricular Remodeling, Exercise and Circulating Metabolites in Volume and Pressure Overload States. JACC: Asia. 2026;6(2):210-24.
5. Wong JJ, Gao F, Lakatta EG, Simonsick E, Ferrucci L, Tan R-S, AlGhatrif M, Koh AS. Skeletal and cardiac muscle longitudinal associations in the Baltimore Longitudinal Study of Aging (BLSA). BMC Medicine. 2026;24(1):317.
6. Yu King Hing N, Wong JJ, Thomson A, Gao F, Teo LLY, Wang Y, Koh AS. Associations between Lipoprotein Subclasses and Cardiovascular Function in Ageing. Phenomics. 2026. 
7. Teow KH, Wong JJ, Zhao Y, Wang LYT, Choo S, Koh AS. Incorporating Implementation Science Into Frailty Interventions for Cardiovascular Disease. JACC: Advances. 2025;4(11, Part 2):102278.
8. Koh JYP, Li S, Koh AS. Precision Measurement of Telomere Length as a Future Guide to Improve CVD Interventions. JAMA Cardiology. 2024;9(3):305-.
9. Zhang H, Leng S, Gao F, Kovalik J-P, Tan R-S, Wee HN, Chua KV, Ching J, Zhao X, Allen J, Wu Q, Leiner T, Zhong L, Koh AS. Longitudinal aortic strain, ventriculo-arterial coupling and fatty acid oxidation: novel insights into human cardiovascular aging. GeroScience. 2024;46(6):5459-71.
10. Tham C-Y, Poon L, Yan T, Koh JYP, Ramlee MK, Teoh VSI, Zhang S, Cai Y, Hong Z, Lee GS, Liu J, Song HW, Hwang WYK, Teh BT, Tan P, Xu L, Koh AS, Osato M, Li S. High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform. Nature Communications. 2023;14(1):281.