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Clin Asst Prof Tan Teck Kiang Malcolm

MBBS, MRCP, M.Med (Int Med)

Senior Consultant

Singapore General Hospital

Specialty: Gastroenterology ＆ Hepatology, Gastroenterology and Hepatology

Clinical Interest: Inflammatory Bowel Disease

Conditions Treated by this Doctor:
Acute ＆ Chronic Viral Hepatitis, Colonoscopy, Colorectal Cancer Screening, Crohn's Disease, Endoscopic Resection of Polyps and Early Cancers, Enteroscopy, Gastroscopy, H. Pylori Infection, Inflammatory Bowel Disease, Liver Cirrhosis, Microscopic colitis, Stomach Cancer Screening, Ulcerative Colitis.

Clinical Appointments

Director Inflammatory Bowel Disease Centre Singapore General Hospital
Senior Consultant Gastroenterology ＆ Hepatology Singapore General Hospital

Academic Appointments

Clinical Senior Lecturer, Yong Loo Lin School of Medicine
Core Faculty, Singhealth Gastroenterology Senior Residency Programme
Clinical Assistant Professor, Duke-NUS Graduate Medical School

Profile

Dr Malcolm Tan graduated from National University of Singapore, Faculty of Medicine in 2005 with MBBS (Singapore). He attained MRCP (UK) and Master of Medicine (Singapore) in 2010. He completed specialist training in Gastroenterology and Hepatology in 2015 and was awarded a Health Manpower Development Plan (HMDP) programme. From 2015 to 2016, he completed an Inflammatory Bowel Disease (IBD) Fellowship at the renowned John Radcliffe Hospital, Oxford University Hospital in Oxford, under the mentorship of Professors Simon Travis and Satish Keshav.

He is the current Chairperson on the Joint Committee on Specialist Training (Gastroenterology) Exit Examination Committee of Singapore and Director of the IBD Service in SGH.

His past and present appointments include being a clinical senior lecturer for Yong Loo Lin School of Medicine, an Assistant Programme Director for the Singhealth Junior Residency Programme for Internal Medicine, and a faculty member in Singhealth Gastroenterology Senior Residency Programme.

He actively participates in teaching medical ethics to specialist trainees under the auspices of Singapore Medical Association Centre for Medical Ethics & Professionalism.

Education

M. Med (Int Med), National University of Singapore, School of Medicine (2010)
MRCP (UK), Royal Colleges of Physicians of the United Kingdom (2010)
MBBS (Singapore), National University of Singapore, School of Medicine (2005)

Professional Appointments and Committee Memberships

Chairperson of Joint Committee on Specialist Training (Gastroenterology) Exit Examination Committee

Awards

Medical ACP Senior Educator Award 2023
Singapore General Hospital Service with a Heart Award 2023
Singhealth Outstanding Faculty Award Academic in Year 2021/2022
Singapore General Hospital Service with a Heart Award 2022
Singhealth Outstanding Faculty Award Academic in Year 2020/2021
Singhealth Outstanding Faculty Award Academic in Year 2017/2018
Awarded Health Manpower Development Plan (HMDP) by Eastern Health Alliance in 2015
Caring Award (Silver) Eastern Health Alliance 2015
Best Educator Award (Medical, Postgraduate (Residency) Eastern Health Alliance 2014
Singhealth Outstanding Faculty Award Academic in Year 2014
Best Educator Award (Medical, Postgraduate (Residency) Eastern Health Alliance 2013
Singhealth Outstanding Faculty Award Academic in Year 2013

Research Interests

Publications

Chong-Teik Lim, Shu-Wen Tay, Sakktivel Elangovan, Wan-Chee Ong , Gek-Hsiang Lim , Ennaliza Salazar , Webber P W Chan , Malcolm T K Tan, Long-term effectiveness and persistence rate of ustekinumab dose intensification in a South East Asian inflammatory bowel disease center J Gastroenterol Hepatol. 2024 Apr 28. doi: 10.1111/jgh.16562. Online ahead of print.
Sim B, Cheah MCC, Chan WPW, Wang YT, Tan M, Hang SK, Salazar. Approximately 1 in 10 Ambulatory Inflammatory Bowel Disease Patients Are At Risk Of Malnutrition – A Prospective Singapore Cohort, J Dig Dis Mar 2023 doi: 10.1111/1751-2980.13165
Qui M, Le Bert N, Chan WPW, Tan M, Hang SK, Hariharaputran S, Sim JXY, Low JGH, Ng W, Wan WY, Ang TL, Bertolett A, Salazar E. Favorable vaccine-induced SARS-CoV-2-specific T cell response profile in patients undergoing immune-modifying therapies. J Clin Invest. 2022 Jun 15;132(12:e159500. doi: 10.1172/JCI159500
Tan Yi Yuan, R Rajesh, Malcolm Tan. Oral faecal microbiota transplantation in ulcerative colitis. Lancet Gastroenterol Hepatol 2022 Apr;7(4):286. doi: 10.1016/S2468-1253(21)00469-6
Shu Wen Tay, Kevin Kim Jun The, Tiing-Leong Ang, Malcolm Tan. Ulcerative colitis: STRIDE-ing beyond symptoms with new standards. Singapore Med J 2021 Nov 26. doi: 10.11622/smedj.2021173.
TL Ang, KW Lim, Daphne Ang, YJ Wong, Malcolm Tan, Andrew Wong. Clinical audit of current Helicobacter pylori treatment outcomes in Singapore. Singapore Med J 2021 Sep. doi: 10.11622/smedj.2021105
Malcolm Tan, Valerie Ng, Chong Teik Lim, Wei-Qiang Leow, Webber Chan. Stringent criteria for withdrawal of biologics in ulcerative colitis. Lancet Gastroenterol Hepatol 2021 Sep;6(9):687-688 doi: 10.1016/S2468-1253(21)00181-3
Yu Jun Wong, Guan Sen Kew, Poh Seng Tan, Zhaojin Chen, Martin Putera, Wenjun Alexander Yip, Tiing Leong Ang, Kwong Ming Fock, Guan Huei Lee, John Hsiang, Daniel Q Huang, Andrew Kwek, Mark D Muthiah, Rahul Kumar, Malcolm Tan, Jessica Tan, Prem Harichander Thurairajah, Eng Kiong Teo, Bee Choo Tai, Seng Gee Lim. Novel albumin, bilirubin and platelet criteria for the exclusion of high-risk varices in compensated advanced chronic liver disease: A validation study. Clin Res Hepatol Gastroenterol. 2021 Nov 26;45(6):101598. doi: 10.1016/j.clinre.2020.101598.
Yi Yuan Tan, Gary Sei Kiat Tay, Yu Jun Wong, James Weiquan Li, Andrew Boon Eu Kwek, Tiing Leong Ang, Lai Mun Wang, Malcolm Teck Kiang Tan. Clinical Features and Predictors of Dysplasia in Proximal Sessile Serrated Lesions. Clin Endosc. 2021 Apr 29. doi: 10.5946/ce.2020.198.
Yu Jun Wong, Malcolm Tan, Qishi Zheng, James Weiquan Li, Rahul Kumar, Kwong Ming Fock, Eng Kiong Teo, Tiing Leong Ang. A systematic review and meta-analysis of the COVID-19 associated liver injury Ann Hepatol Aug 31;S1665-2681(20)30161-7. doi: 10.1016/j.aohep.2020.08.064.
Kevin Kim Jun Teh , Shu Wen Tay , Kaina Chen , Samantha Jingyun Koh , Yu Jun Wong , Andrew Boon Eu Kwek , James Weiquan Li , Kwong Ming Fock , Eng Kiong Teo , Tiing Leong Ang , Malcolm Teck Kiang Tan. Impact of Enhanced Personal Protective Equipment on Colonoscopy Performance During the COVID-19 Pandemic. Endosc Int Open. 2020 Jun;8(6):E809-E814. doi: 10.1055/a-1167-1703. Epub 2020 Jun 2.
Hussain I, Tan M, Veeraraghavan MA, Wang LM, Kwek AEB. Endosonographic Appearances of a Rare Duodenal Tumour, Brunner's Gland Hamartoma. Case Rep Gastroenterol. 2019 Jul 16;13(2):310-320. doi: 10.1159/000501674.
Stephanie M Slevin, Lucy C Garner, Conor Lahiff, Malcolm Tan, Lai Mun Wang, Helen Ferry, Borgel Greenaway, Kate Lynch, Alessandra Geremia, Stephen Hughes, Karen Leavens, David Krull, Daniel J B Marks, Katherine Nevin, Kevin Page, Naren Srinivasan, Ruth Tarzi, Paul Klenerman , Simon Travis, Carolina V Arancibia-Cárcamo, Satish Keshav. Lymphocyte Activation Gene (LAG)-3 Is Associated With Mucosal Inflammation and Disease Activity in Ulcerative Colitis. J Crohns Colitis. 2020 Mar 16;jjaa054. doi: 10.1093/ecco-jcc/jjaa054.
James Weiquan Li, Tiing Leong Ang, Lai Mun Wang, Andrew Boon Eu Kwek, Malcolm Teck Kiang Tan, Kwong Ming Fock, Eng Kiong Teo. Endoscopic submucosal dissection of colorectal neoplasms: an audit of its safety and efficacy in a single tertiary centre in Singapore. Singapore Med J 2019; 60(10): 526-531
Ang TL, Li JW, Wong YJ, Tan YJ, Fock KM, Tan MTK, Kwek ABE, Teo EK, Ang DS, Wang LM. A prospective randomized study of colonoscopy using blue laser imaging and white light imaging in detection and differentiation of colonic polyps.Endosc Int Open. 2019 Oct;7(10):E1207-E1213
Malcolm Tan, Lydia White. Book Chapter “Inpatient Care”, Inflammatory Bowel Disease Nursing Manual, Springer Nature Switzerland 2019, pp 423-433
S Slevin; M Tan; C Lahiff; K Williamson; A Geremia; S Hughes; K Leavens; K Nevin; D J B Marks; R Tarzi; N Srinivasan; C Arancibia; S Keshav. P064 Intestinal expression of LAG-3 correlates with inflammatory activity and response to biological therapy in ulcerative colitis. Journal of Crohn's and Colitis, Volume 12, Issue supplement_1, 16 January 2018, Pages S125
Wong YJ, Irani FG, Tan M, Teo M. Massive upper gastrointestinal bleeding post-Whipple's surgery from anastomotic varices due to mesenteric hypertension. Endoscopy. 2018 Jul;50(7):E159-E162. doi: 10.1055/a-0595-7507. Epub 2018 May 9.
Tan M, East JE. Fitting Balloon Overtube-Assisted Colonoscopy (BOAC) Into the Difficult or Failed Colonoscopy Algorithm. Clin Gastroenterol Hepatol. 2018 Apr;16(4):594-595. doi: 10.1016/j.cgh.2017.11.035
Tan M, Lahiff C, Bassett P, Bailey AA, East JE. Efficacy of Balloon Overtube-Assisted Colonoscopy In Patients With Incomplete or Previous Difficult Colonoscopies: A Meta-Analysis. Clin Gastroenterol Hepatol. 2017 Oct;15(10):1628-1630
Kumar R, Kwek A,Tan M, Fock KM, Ang TL. Sa1187 Outcomes of Intensive Care Unit (ICU) Patients With Cholangitis Requiring Percutaneous Transhepatic Biliary Drainage (PTBD) and Endoscopic Retrograde Cholangiopancreaticography (ERCP). Gastrointestinal Endoscopy.83(5):AB247-AB8.
Li JW, Tan MTK, Ang TL, Teo EK. Chemoprevention trials of GI cancers in Asia. Best Practice & Research Clinical Gastroenterology.29(6):967-78. Dec 2015.
Ang TL, Fock KM, Tan MT, Assam PN, Chan ES. Impact of Asia-Pacific guidelines on gastric cancer and Helicobacter pylori infection on prevailing clinical practices. J Dig Dis. Feb 2016;17(2):122-7.
Tan M. Importance of defining loss of response before therapeutic drug monitoring. Gut. 2015;64(3):516-7.Mar 2015
Tan M, Ong JP, Teo EK. Achieving deep remission in Crohn's disease: treating beyond symptoms. Annals of the Academy of Medicine, Singapore. Apr 2014;43(4):200-2.

Research Trials

Tags: Gastroenterology ＆ Hepatology, Gastroenterology and Hepatology, Inflammatory Bowel Disease, Acute ＆ Chronic Viral Hepatitis, Colonoscopy, Colorectal Cancer Screening, Crohn's Disease, Endoscopic Resection of Polyps and Early Cancers, Enteroscopy, Gastroscopy, H. Pylori Infection, Inflammatory Bowel Disease, Liver Cirrhosis, Microscopic colitis, Stomach Cancer Screening, Ulcerative Colitis