Skip Ribbon Commands
Skip to main content
Menu

Adj Asst Prof Tan Boon Yew

Clinical Appointments

  • Senior Consultant Department of Cardiology National Heart Centre SingaporeNational Heart Centre Singapore

Profile

​Adjunct Assistant Professor Tan Boon Yew is a Senior Consultant with the Department of Cardiology at the National Heart Centre Singapore. His sub-specialty interest is in electrophysiology and pacing.

Education

  • CCDS 2010
  • FAMS 2006
  • MRCP (UK) 2002
  • MB ChB University of Sheffield (UK) 1997

Professional Appointments and Committee Memberships

  • Senior Consultant, Department of Cardiology, National Heart Centre Singapore 2012 - Present
  • Clinical Assistant Professor, Duke-NUS Medical School

Awards

  • Health Manpower Development Plan (HMDP) Fellowship, Electrophysiology Fellow, Johns Hopkins Hospital, Baltimore. 2008-2009
  • National Medical Research Council (NMRC) Research Training Fellowship, Post-Doctorate Research Fellow,Johns Hopkins University, School of Medicine, Baltimore. 2009-2010
  • Singapore Medical Journal Best Research Paper Award 2010, Second Prize 

Research Interests

Publications and Research Trials

  • Case Report: Ventricular tachycardia with therapy inappropriately withheld due to ventricular based timing. Tan, Weixian & Lim, Tien & Heo, Rachel & Ching, Chi & Tan, Boon Yew. HeartRhythm Case Reports. 2020. 10.1016/j.hrcr.2020.06.009.
  • The application of exercise stress cardiovascular magnetic resonance in patients with suspected dilated cardiomyopathy. Le, Thu-Thao & Bryant, Jennifer & Ang, Briana & Pua, Chee & Su, Boyang & Ho, Pei & Lim, Shiqi & Huang, Weiting & Lee, Phong & Tang, Hak & Chin, Chee Tang & Tan, Boon Yew & Cook, Stuart & Chin, Calvin. Journal of Cardiovascular Magnetic Resonance. 2020. 22. 10. 10.1186/s12968-020-0598-4.
  • Prevalence of Brugada Syndrome in a Large Population of Young Singaporean Men. Shen, Xiayan & Tan, Benjamin & Sia, Ching-Hui & Lee, Joshua & Dalakoti, Mayank & Wang, Kangjie & Lim, Daniel & Sng, Gerald & Lee, Edward & Chow, Weien & Kwan, Clarence & Wang, Luo & Tan, Boon Yew & Lim, Paul & Chua, Kelvin & Ho, Kah & Lim, Eric & Ching, Chi-Keong & Teo, Wee & Chong, Daniel. Circulation. 2020. 141. 155-157. 10.1161/CIRCULATIONAHA.119.043670.
  • Identification of an INa-dependent and Ito-mediated proarrhythmic mechanism in cardiomyocytes derived from pluripotent stem cells of a Brugada syndrome patient. Ma, Dongrui & Liu, Zhenfeng & Loh, Li & Zhao, Yongxing & li, Guang & Liew, Reginald & Islam, Omedul & Wu, Jianjun & Chung, Ying & Teo, Wee & Ching, Chi & Tan, Boon Yew & Chong, Daniel & Ho, Kah & Lim, Paul & Yong, Rita & Panama, Brian & Kaplan, Aaron & Bett, Glenna & Wei, Heming. Scientific Reports. 2020. 8. 10.1038/s41598-018-29574-5.
  • ‘Balanced ischaemia’ on ECG in dual territory STEMI. Balakrishnan, Iswaree & Chin, Chee & Teo, Louis & Tan, Boon Yew & Yeo, Khung. Oxford Medical Case Reports. 2018. 10.1093/omcr/omy043.
  • A novel three base-pair deletion in domain two of the cardiac sodium channel causes Brugada syndrome. Tan, Boon Yew & Wang, Luokai & Uttamchandani, Mahesh & Barajas Martinez, Hector & Dumaine, Robert & Morin, Nathalie & Ching, Chi & Ho, Kah & Chong, Daniel & Chow, Weien & Yap, Eric & Moochhala, Shabbir & Hu, Dan & Yong, Rita & Teo, Wee. Journal of Electrocardiology. 2018. 51. 10.1016/j.jelectrocard.2018.03.009.
  • Implantation of a dual-chamber permanent pacemaker in a pregnant patient guided by intra-cardiac echocardiography and electro-anatomic mapping. Chua, Kelvin & Lim, Eric & Chong, Daniel & Tan, Boon Yew & Ho, Kah & Ching, Chi. HeartRhythm Case Reports. 2017. 3. 10.1016/j.hrcr.2017.09.003.
  • “BALANCED ISCHEMIA” ON ECG IN DUAL TERRITORY STEMI. Balakrishnan, Iswaree & Chin, Chee & Teo, Louis & Tan, Boon Yew & Yeo, Khung. Journal of the American College of Cardiology. 2017. 69. 2130. 10.1016/S0735-1097(17)35519-5.
  • Remote magnetic catheter navigation versus conventional ablation in atrial fibrillation ablation: Fluoroscopy reduction. Lim, Paul & Toh, Joseph & Loh, Julian & Lee, Edward & Chong, Daniel & Tan, Boon Yew & Ho, Kah & Ching, Chi & Teo, Wee. Journal of Arrhythmia. 2017. 33. 10.1016/j.joa.2016.08.007.
  • Remote monitoring of patients with cardiac implantable electronic devices: a Southeast Asian, single-centre pilot study. Lim, Paul & Lee, Audry & Chua, Kelvin & Lim, Eric & Chong, Daniel & Tan, Boon Yew & Ho, Kah & Teo, Ws & Ching, Chi.  Singapore Medical Journal. 2016. 57. 372-377. 10.11622/smedj.2016120.
  • Non-fluoroscopic navigation systems for radiofrequency catheter ablation of supraventricular tachycardia reduces ionising radiation exposure. See, Jason & Amora, Jonah & Lee, Sheldon & Lim, Paul & Teo, Ws & Tan, Boon Yew & Ho, Kah & Lee, Chee & Ching, Chi-Keong. Singapore medical journal. 2016. 57. 10.11622/smedj.2016017.
  • Paroxysmal Supraventricular Tachycardia With Ventriculoatrial Block and QRS Duration Shortening: What Is the Mechanism?. Lim, Paul & Chong, Daniel & Tan, Boon Yew & Ho, Kah & Teo, Ws & Ching, Chi. Journal of cardiovascular electrophysiology. 2015. 27. 10.1111/jce.12878.
  • Paroxysmal Supraventricular Tachycardia With Ventriculoatrial Block and QRS Duration Shortening: What Is the Mechanism?. Lim, Paul & Chong, Daniel & Tan, Boon Yew & Ho, Kah & Teo, Ws & Ching, Chi. Journal of cardiovascular electrophysiology. 2015. 27. 10.1111/jce.12878.
  • Initial experience of subcutaneous implantable cardioverter defibrillators in Singapore: A case series and review of the literature. Lim, Tien & Tan, Boon Yew & Ho, Kah & Lim, Chuh & Teo, Ws & Ching, Chi-Keong. Singapore medical journal. 2015. 56. 580-585. 10.11622/smedj.2015154.
  • A Brugada syndrome proband with compound heterozygote SCN5A mutations identified from a Chinese family in Singapore. Tan, Boon Yew & Yong, Rita & Barajas Martinez, Hector & Dumaine, Robert & Chew, Ying & Wasan, Pavandip & Ching, Chi & Ho, Kah & Gan, Linda & Morin, Nathalie & Chong, Alicia & Yap, Shiao Hui & Neo, Jia & Yap, Eric & Moochhala, Shabbir & Chong, Daniel & Chow, Weien & Seow, Swee & Hu, Dan & Teo, Ws. Europace. 2015. 18.10.1093/europace/euv058.
  • Pacemaker Failure Due to Loss of Fluid Seal in a Patient with a 5/6mm Pacemaker Header Port and a 5mm Unipolar Lead. Lim, Paul & Tan, Boon Yew & Ho, Kah & Ching, Chee & Teo, Ws. Indian pacing and electrophysiology journal. 2013.13. 217-220. 10.1016/S0972-6292(16)30691-X.
  • Trends Amongst Implantable Cardioverter Defibrillator Patients in a Tertiary Cardiac Centre in Singapore from 2002 to 2011. Chong, Daniel & Tan, Boon Yew & Ho, Kah & Teo, Ws & Ching, Chi. Annals of the Academy of Medicine, Singapore. 2013. 42. 480-2.
  • Authors' response to the correspondence entitled 'Too ill for an implantable cardioverter defibrillator?'. Chong, Daniel & Tan, Boon Yew & Ho, Kah & Teo, Ws & Ching, Chi. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2013. 15. 10.1093/europace/eut205.
  • A Clinical Approach to a Family History of Sudden Death. Tan, Boon Yew & Judge, Daniel. Circulation. 2012. Cardiovascular genetics. 5. 697-705. 10.1161/CIRCGENETICS.110.959437.
  • Right Pace, Wrong Place. Lim, Choon & Yeo, Khung & Tan, Boon Yew & Liew, Reginald & Tan, Jack. Annals of the Academy of Medicine, Singapore. 2012. 41. 417-9.
  • Clinical markers of organ dysfunction associated with increased 1-year mortality post-implantable cardioverter defibrillator implantation. Chong, Daniel & Tan, Boon Yew & Ho, Kah & Liew, Reginald & Teo, Ws & Ching, Chi. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2012. 15. 10.1093/europace/eus225.
  • Fragmented QRS complexes predict right ventricular dysfunction and outflow tract aneurysms in patients with repaired tetralogy of Fallot. Shanmugam, Nesan & Yap, Jonathan & Tan, Ru San & Le, Thu-Thao & Gao, Fei & Chan, Jia & Chong, Daniel & Ho, Kah & Tan, Boon Yew & Ching, Chi & Teo, Ws & Tan, Ju & Liew, Reginald. International journal of cardiology. 2012. 167. 10.1016/j.ijcard.2012.04.004.
  • Electrophysiological Characteristics of Patients Who Undergo Two Or More Ablations for Atrial Fibrillation. Fam, Jiang & Chong, Daniel & Liew, Reginald & Tan, Boon Yew & Teo, Ws & Ching, Chi. Journal of Arrhythmia. 2011. 27. PE2_011. 10.4020/jhrs.27.PE2_011.
  • In Secondary Prevention ICD Patients, Does the Initial Presenting VT Cycle Length Predict Subsequent Cycle Length of VT Episodes?. Chong, Daniel & Malik, Amit & Tan, Boon Yew & Liew, Reginald & Teo, Ws & Ching, Chi. Journal of Arrhythmia. 2011. 27. PE4_083. 10.4020/jhrs.27.PE4_083.
  • In a Multi-Ethnic Pacemaker Population, Are There Age Related, Gender or Ethnic Differences in Intracardiac Electrogram Amplitudes?. Chong, Daniel & Malik, Amit & Tan, Boon Yew & Liew, Reginald & Ching, Chi & Teo, Ws. Journal of Arrhythmia. 2011. 27. PE4_044. 10.4020/jhrs.27.PE4_044.
  • Brugada Syndrome and SCN5A-Encoded Cardiac Sodium Channel Mutations in Singapore. Tan, Boon Yew & Yong, Rita & Uttamchandani, Mahesh & Wong, Wei & Liew, Reginald & Chong, Daniel & Seow, Swee & Neo, Jia & Yap, Shiao Hui & Gan, Linda & Ching, Chi & Teo, Ws. Journal of Arrhythmia. 2011. 27. PE3_012. 10.4020/jhrs.27.PE3_012.
  • Efficacy of Ventricular Capture Management in Patients with Single or Dual Chamber Pacemakers. Chong, Hui & Liang, Shufen & Malik, Amit & Chong, Daniel & Tan, Boon Yew & Liew, Reginald & Teo, Ws & Ching, Chi. Journal of Arrhythmia. 2011. 27. PE4_084. 10.4020/jhrs.27.PE4_084.
  • EndoEpicardial Ablation of Recurrent Ventricular Tachycardia Using Remote Magnetic Navigation System (Stereotaxis). Malik, Amit & Teo, Ws & Ching, Chi & Liew, Reginald & Tan, Boon Yew & Chong, Daniel. Journal of Arrhythmia. 27. 2011. OP66_5. 10.4020/jhrs.27.OP66_5.
  • Compound Heterozygosity in Brugada Syndrome: A Case Study. Tan, Boon Yew & Yong, Rita & Uttamchandani, Mahesh & Wong, Wei & Liew, Reginald & Chong, Daniel & Seow, Swee & Neo, Jia & Yap, Shiao Hui & Gan, Linda & Ching, Chi & Teo, Ws. Journal of Arrhythmia. 2011. 27. PE3_011. 10.4020/jhrs.27.PE3_011.
  • Pacing Trends over a Decade in a National Registry. Teo, Ws & Amit, Malik & Tan, Boon Yew & Chong, Daniel & Lie, Reginald & Ching, Chi & Sim, Ling. Journal of Arrhythmia. 2011. 27. PE4_043. 10.4020/jhrs.27.PE4_043.
  • Use of Support Catheter for LV Lead Placement in Challenging Biventricular Implant. Malik, Amit & Teo, Ws & Ching, Chi & Liew, Reginald & Tan, Boon Yew & Chong, Daniel & Chin, Chee & Ang, Chin. Journal of Arrhythmia. 2011. 27. PE4_087. 10.4020/jhrs.27.PE4_087.
  • In a Multi-Ethnic Asian ICD Population, Are There Differences in Anti-Tachycardia Pacing Thresholds?. Koh, Aaron & Chong, Daniel & Tan, Boon Yew & Liew, Reginald & Ching, Chi & Teo, Ws. Journal of Arrhythmia. 2011. 27. PE3_016. 10.4020/jhrs.27.PE3_016.
  • Shared Desmosome Gene Findings in Early and Late Onset Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy. Boon Yew Tan, MBChB, Rahul Jain, MD, A. Dénise den Haan, MD, Yan Chen, MD, PhD, Darshan Dalal, MBBS, PhD, Harikrishna Tandri, MD, Nuria Amat-Alarcon, MS, Amy Daly, MS, Crystal Tichnell, MGC, Cynthia James, PhD, Hugh Calkins, MD, Daniel P. Judge, MD.  Journal of Cardiovascular Translational Research 2010;3: 663-673.
  • Novel Electrocardiogram device with Web based service centre for ambulatory ECG monitoring study (NEW). Tan Boon Yew, Ho Kah Leng, Ching Chi Keong, Teo Wee Siong.  Singapore Medical Journal 2010;51(7):565-569.
  • Electrocardiographic Features of Arrhythmogenic Right Ventricular Dysplasia. Rahul Jain MD, Darshan Dalal MD, Amy Daly MS, Crystal Tichnell MGC, Cynthia James PhD, Ariana Evenson MHSA, Rohit Jain MD, Theodore Abraham MD, Boon Yew Tan MBChB, Hari Tandri MD, Stuart D. Russell MD, Daniel Judge MD, and Hugh Calkins MD.  Circulation 2009;120: 477-487.
  • Comprehensive Desmosome Mutation Analysis in North Americans With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy. den Haan, A Denise MD; Tan, Boon Yew MBChB; Zikusoka, Michelle N. MD; Llado, Laura Ibanez MS; Jain, Rahul MD; Daly, Amy MS; Tichnell, Crystal MGC; James, Cynthia PhD; Amat-Alarcon, Nuria MS; Abraham, Theodore MD; Russell, Stuart D. MD; Bluemke, David A. MD, PhD; Calkins, Hugh MD; Dalal, Darshan MD, PhD; Judge, Daniel P. MD.  Circulation: Cardiovascular Genetics 2009;2(5):428-435. 
  • Right pace, wrong place. Choon Pin Lim, Khung Keong Yeo, Boon Yew Tan, Reginald Liew, Jack WC Tan. J Huangzhong Univ Sci Technology Med Sci 2008;28(6):639-644.
  • A Brugada syndrome proband with compound heterozygous SCN5A mutations identified from a Chinese family in Singapore. Boon Yew Tan, Rita Yu Yin Yong, Hector Barajas-Martinez, Robert Dumaine, Ying Xia Chew, Pavandip Singh Wasan, Chi keong Ching, Kah Leng Ho, Linda Seo Hwee Gan, Nathalie Morin, Alicia Poh Leong Chong, Shio Hui Yap, Jia ling Neo, Eric Peng Huat Yap, Swee Chong Seow, Dan hu, Mahesh Uttamchandani, Wee Siong Teo.  Europace: Under Review.

Research Trials

  • Investigating cardiac arrhythmias: Long QT syndrome and Brugada syndrome.
  • Regional registry of Brugada syndrome.
  • Microvolt T-wave alternans as a potential diagnostic tool for Brugada syndrome.
  • Brugada syndrome: An in vitro humanized disease modeling with iPSC approach.