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Clin Assoc Prof Keng Yung Jih Felix

Clin Assoc Prof Keng Yung Jih Felix

MBBS, MRCP(UK), MMed (Int Med), FRCP (London), FAPSC, FAMS (Cardiology), FASNC, CBNC, CBCCT

Senior Consultant

National Heart Centre Singapore

Specialty: Cardiology

Sub-specialties: Nuclear Cardiology

Clinical Appointments

  • Senior Consultant & Director, Nuclear Cardiac Imaging Department of Cardiology National Heart Centre SingaporeNational Heart Centre Singapore


Clinical Associate Professor Felix Keng is a Senior Consultant with the Department of Cardiology and the Director of Nuclear Cardiac Imaging at the National Heart Centre Singapore. His sub-specialty interest is in nuclear cardiology and cardiac computed tomography. He regularly lectures for the International Atomic Energy Agency in countries around the world.

Clin Assoc Prof Keng received his Certification in Nuclear Cardiology from the Certification Board of Nuclear Cardiology, USA in 1998. He also received Board Certification in Cardiac CT in 2010.
Clin Assoc Prof Keng did his fellowship at the Methodist Hospital, Baylor College of Medicine and at the UCLA Pet Centre, USA. For his Cardiac CT fellowship, he visited the University of Erlangen and Klinikum Pasing, Munich, Germany and University of California, Irvine, USA. He is a Fellow of the Royal College of Physicians, Edinburgh, UK; Fellow of the Royal College of Physicians, London, UK; Fellow of the Academy of Medicine (Cardiology), Singapore and Fellow of the Asia Pacific Society of Cardiology (FAPSC) since 2007.


  • CBNC
  • FAMS (Cardiology)
  • FRCP (London)
  • M Med (Int Med)
  • MRCP (UK) (Int Med) 
  • MBBS

Professional Appointments and Committee Memberships

  • Clinical Associate Professor, Duke-NUS Medical School, 2019 to Present​
  • Senior Consultant, Department of Cardiology, National Heart Centre Singapore
  • Director, Nuclear Cardiac Imaging, National Heart Centre Singapore
  • Visiting Consultant, International Atomic Energy Agency
  • International Advisory Panel, American Society of Nuclear Cardiology
  • Fellow, Academy of Medicine Singapore
  • Fellow, Royal College of Physicians, London
  • Fellow, American Society of Nuclear Cardiology
  • Fellow, Asia Pacific Society of Cardiology
  • Member, Quality Assurance Committee, Singapore General Hospital
  • Member, Quality Assurance Committee, National Heart Centre Singapore
  • Member, Patient Safety Committee, Singapore General Hospital
  • Member, International Society of Cardiovascular Pharmacology
  • Member, Singapore Medical Association
  • Panel Member, MOH Haze Advisory
  • Member, Outram Campus Emergency Planning Committee
  • Past Secretary, Asia Pacific Society of Nuclear Cardiology
  • Board Member, Annals, Academy of Medicine, Singapore
  • Journal Reviewer, Archives of Medical Research
  • Journal Reviewer, Singapore Medical Journal


  • Letter of Appreciation, Central Manpower Base, Ministry of Defence
  • Letter of Appreciation, XVII Southeast Asia Games, SEA Games Federation
  • Excellence Award, Defence Administration Group, Ministry of Defence
  • The Young Investigator Award, 5th International Conference of Nuclear Cardiology
  • Best National Abstract, 5th International Conference of Nuclear Cardiology
  • ASNC/Fujisawa Healthcare Travel Award 2001
  • HMDP (Nuclear Cardiology & Cardiac CT)
    • Baylor College of Medicine, Houston, Texas, USA (Cardiac SPECT Imaging)
    • University of California, Los Angeles, USA (Cardiac PET Imaging)
    • Universitatsklinikum Erlangen, Germany (Cardiac CT)
    • Klinikum Munich Pasing, University of Munich, Germany (Cardiac CT)
    • University of California, Irvine, USA (Cardiac CT)

Research Interests


Book Chapter

  • Assessment of myocardial Viability by Radionuclide Techniques. R Campisi, F Keng, HR Schelbert. Book Chapter. Diagnostic Nuclear Medicine, 2nd Revised Edition Springer 2006, pp 39-59


  • Gated myocardial perfusion tomography for the assessment of left ventricular function and volumes: Comparison with echocardiography. Cwajg E, Cwajg J, He ZX, Hwang WS, Keng F, Nagueh SF, Verani MS. J Nucl Med 1999;40:1857-1865
  • Technetium-99m sestamibi for the assessment of myocardial salvage following reperfusion therapy in acute myocardial infarction. F Keng, T Chua, A Goh, ES Ang, FX Sundram, A Tan. Ann Acad Med Singapore 2000;29:224-30
  • Comparison of global and regional left ventricular function assessed by gated-SPECT and 2-D echocardiography. E Cwajg, J Cwajg, F Keng, ZX He, MS Verani. Rev Port Cardiol 2000;19 Suppl1:I39-46
  • Altered adrenergic receptor density in myocardial hibernation in humans : A possible mechanism of depressed myocardial function. K Shan, RJ Bick, BJ Poindexter, SF Nagueh, S Shimoni, MS Verani, F Keng, MJ Reardon, GV Letsou, JF Howell, WA Zoghbi. Circulation 2000;102:2599-2606
  • Abnormal longitudinal, base-to-apex myocardial perfusion gradient by quantitative blood flow measurement in patients with coronary risk factors. MH Pampaloni, F Keng, T Kudo, JS Sayre, HR Schelbert. Circulation 2001;104:527-532
  • Gated Single-Photon Emission Computed Tomography in Patients With Hypertrophic Obstructive Cardiomyopathy Undergoing Transcoronary Ethanol Septal Ablation. Felix Y.J. Keng, Su Min Chang, Eduardo Cwajg, Zuo-Xiang He, Nasser M. Lakkis, Sherif F. Nagueh, William H. Spencer III, Mario S. Verani. J Nucl Cardiol 2002;9:594-600
  • Cardiac PET: A Review. Felix Y.J. Keng. Ann Acad Med 2004;33:175-82
  • Nuclear Cardiology in Singapore: A Review. CK Ching, F Keng, TSJ Chua. Ann Acad Med 2004;33:461-3
  • A Multinational Study to Establish the Value of Early Adenosine Technetium-99m Sestamibi Myocardial Perfusion Imaging in Identifying a Low-Risk Group for Early Hospital Discharge After Acute Myocardial Infarction. JJ Mahmarian, LJ Shaw, NG Filipchuk, HA Dakik,, SS Iskander, TD Ruddy, M Henzlova, F Keng, A Allam, LA Moye, CM Pratt for the INSPIRE Investigators. J Am Coll Cardiol 2006;48:2448-57.
  • An Initial Strategy of Intensive Medical Therapy is Comparable to That of Coronary Revascularization for Suppression of Scintigraphic Ischemia in High- Risk but Stable Survivors of Acute Myocardial Infarction. JJ Mahmarian, HA Dakik, NG Filipchuk, LJ Shaw, SS Iskander, TD Ruddy, F Keng, M Henzlova, A Allam, LA Moye, CM Pratt for the INSPIRE Investigators. J Am Coll Cardiol 2006;48:2458-67.
  • Nitrate-augmented myocardial perfusion imaging for assessment of myocardial viability: recent advances. MF Yang, F Keng, ZX He. Nucl Med Commun 2009;30:415-419

Research Trials

  • Principal Investigator (Singapore), INSPIRE Trial
  • Principal Investigator (Singapore), IAEA Nitrate Augmented Myocardial Viability Trial (NAMSY), Core Nuclear Laboratory, Expert Advisor
  • Principal Investigator (Singapore), CVT 5131
  • Principal Investigator, Telmisartan BI 502.480 & BI 502.491 Trial
  • Principal Investigator, BMS Cardiolite 301 Trial (Kawasaki Disease)
  • Co-Investigator, STICH Trial
  • Co-Investigator, PLATO Trial
  • Co-Investigator, Rocket AF Trial