Researcher Profile: Prof Derek Hausenloy

Prof Derek Hausenloy

Clinician Scientist & Senior Consultant, Cardiology
National Heart Centre Singapore

Prof Derek Hausenloy is a Clinician Scientist with the SingHealth Duke-NUS Academic Clinical Programme and a Senior Consultant with the Department of Cardiology at the National Heart Centre Singapore. He is also Professor, Cardiovascular & Metabolic Disorders Programme, Duke-NUS Medical School and Professor of Cardiovascular Medicine, University College London.

Prof Hausenloy conducts both basic and clinical research in the area of ischaemic heart disease and heart failure. His research focus is on discovering novel therapies for protecting the heart against the detrimental effects of acute ischaemia/reperfusion injury (IRI) in order to prevent the onset of heart failure. He uses a translational approach to cardioprotection ranging from experimental models of acute IRI to proof-of-concept clinical studies in acute myocardial infarction and cardiac bypass surgery patients, and finally to large multi-center randomised clinical trials focused on clinical outcomes. He is also interested in both small animal and clinical cardiac PET and MRI imaging in the context of acute myocardial infarction and cardioprotection.

Prof Hausenloy has been the principal investigator on over 20 research grants, and he has authored over 170 papers.

APPOINTMENTS

Clinician Scientist & Senior Consultant, National Heart Centre Singapore
Professor, Programme in Cardiovascular & Metabolic Disorders, Duke-NUS Medical School, Singapore
Professor of Cardiovascular Medicine, University College London, UK

PUBLICATIONS

White SK, Davies JR, Sado DM, Maestrini V, Fontana M, Treibel TA, Tehrani S, Flett AS, Froehlich GM, Meier P, Ariti C, Moon JC, Yellon DM, Hausenloy DJ. Remote ischaemic conditioning reduces myocardial infarct size in patients with ST-segment elevation myocardial infarction: The ERIC-STEMI trial. JACC Cardiovasc Interv. 2015 Jan;8(1 Pt B):178-88.IF 7.440
Yellon DM, Ackbarkhan A, Balgobin V, Bulluck H, Deelchand A, Dhuny M, Domah N, Gaoneadry D, Jagessur RK, Joonas N, Kowlessur S, Lutchoo J, Nicholas J, Pauvaday K, Shamloll O, Walker JM, Hausenloy DJ. Remote ischemic conditioning reduces myocardial infarct size in STEMI patients treated by thrombolysis: The ERIC-LYSIS study. JACC 2015 Jun 30;65(25):2764-5. IF 16.503
Hausenloy DJ, Kharbanda R, Schmidt MR, Møller UK, Ravkilde J, Jensen LO, Engstrøm T, García Ruiz JM, Radovanovic N, Christensen EF, Sørensen HT, Ramlall M, Bulluck H, Evans R, Nicholas J, Knight R, ClaytonT, Yellon DM, Bøtker HE. Effect of remote ischemic conditioning on clinical outcomes in patients presenting with a ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Eur Heart J. 2015 Aug 1;36(29):1846-8.. IF 14.723
Hausenloy DJ, Yellon DM. Targeting Myocardial Reperfusion Injury--The Search Continues. N Engl J Med. 2015 Sep 10;373(11):1073-5. IF 55.873
Hausenloy DJ, Candilio L, Evans R, Ariti C, Jenkins DP, Kolvekar S, Knight R, Kunst G, Laing C, Nicholas J, Pepper J, Robertson N, Xenou X, Clayton T, Yellon DM. Remote Ischemic Preconditioning and Outcomes in Cardiac Bypass Surgery. N Engl J Med 2015 Oct 8. IF 55.873.

AWARDS & ACHIEVEMENTS

NMRC Clinical Trial Grant $1.72 million (2016)
European Society of Cardiology Outstanding Achievement Award (2013)
Winner of the British Society of Cardiovascular ResearchSCR Marshall Research Excellence Award (2012)
Winner of Young Investigator Award, British Cardiac Society, Glasgow (2006)
Winner of International Society of Heart Research-Servier Research Fellowship (2006)