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Clinical Trials and Translational Research

The National Heart Centre Singapore (NHCS) has established itself as one of the leading sites for cardiovascular clinical trials and translational research in Singapore. We consistently strive to improve patients' care through interdisciplinary studies in all areas of cardiovascular research. As a regional center for cardiovascular medicine, our highly experience clinicians, researchers and study management team works closely with pharmaceutical, biotech, medical devices companies and academic institutions to achieve and advance our knowledge in biomedical science and translate to potential innovative treatments & better patient care.

Clinical & Translational Research Office (CTRO) has been established since 1999 to provide support for collaboration between our clinical research team and various external partners, which allows us to develop advance cutting edge human research. To date, we have conducted 300 over clinical trials and IIT projects.

​Type of studies:

  • Investigator-initiated studies
  • Industry-sponsored clinical studies
  • Interventional and non-interventional clinical studies
  • Observational studies

Areas of Clinical Research (Presently Available)

  • ​Pulmonary Arterial Hypertension
  • Coronary Artery Disease
  • High Cholesterol
  • Heart Failure
  • Congenital Heart Disease
  • Infective Endocarditis
  • Valvular Heart Disease
  • Angina
  • Chronic Kidney Disease
  • Arrhythmia
  • Myocardial Infarction
  • Diabetes
  • Hypertensive Heart Disease
  • Obesity
  • Healthy Volunteer

What to Expect from Clinical Research?

What is a clinical research?

A clinical research is any scientific investigation in human subjects that are intended to discover or determine the safety and effectiveness of medications, devices, diagnostic tools and treatment to benefit patients.

There may be treatment involved in a Clinical research. If you have agreed to partake in the clinical research, you are required to sign an informed consent form before any research procedures were to take place. If you agree to participate in this study, you should be prepared to undergo all the research procedures. You are required to keep your study appointment. If it is necessary to miss an appointment, please contact the study staff to reschedule as soon as you know you will miss the appointment. Your doctor or Principal Investigator may stop you from participation in the clinical research at any time for safety and other relevant reasons.

Why should you participate in a clinical research?

You can decide to participate in a clinical research because:
  1. You want to play a part in research that improves health and receive information.
  2. You want contribute in research for future generations.
  3. You are seeking for alternative treatments which are currently not available and/or not effective.

What are my rights?

In Clinical Research participation, you have the rights to:
  1. You can ask questions regarding the clinical research before partaking in it.
  2. Time will be given for you to make a decision in partaking in the clinical research.
  3. You can withdraw from the clinical research after participation.
  4. Receive any new information regarding the procedures involved, new changes, potential risks and benefits of the clinical research.

Your protection by Ethics Committee

Ethics Committee is a review board or a committee that comprises of medical and non-medical professionals to ensure your rights, safety and well-being are protected in a clinical research. The ethics committee will also provide reviews and approval on the clinical research that will be conducted on human subjects.
Please contact the following personnel to discuss on potential research collaboration & partnership or any enquiry regarding our services:
Ms Leow Wanshan:

Research Recruitment

Click here for information on the latest research recruitment at NHCS.