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Assoc Prof Wong En Hou Philip from National Heart Centre Singapore

Assoc Prof Wong En Hou Philip

​MBBS, MRCP(UK), FRCP, FAMS

Senior Consultant

National Heart Centre Singapore

Specialty: Cardiology

Sub-specialties: Interventional Cardiology

Clinical Appointments

  • Senior Consultant Department of Cardiology National Heart Centre SingaporeNational Heart Centre Singapore

Academic Appointments

  • Research EXCO SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme

Profile

​Associate Professor Philip Wong is a Senior Consultant with the Department of Cardiology and Deputy Director of the National Heart Research Institute Singapore at the National Heart Centre Singapore. His research interest include Health Technology, Digital Health and Medical Devices, including innovation, pre-clinical development and commercialization. He has 14 filed patents and has succesfully spinned off two companies from within the Academic Centre.

Education

  • FACC 2005
  • FRCP 2004
  • FAMS 2003
  • MRCP (UK) 1995
  • MBBS (S’pore) 1989

Professional Appointments and Committee Memberships

  • Senior Consultant, Department of Cardiology, National Heart Centre Singapore 2005 - Present
  • Research EXCO, Cardiovascular Sciences Academic Clinical Programme 2013 - Present
  • Fellow, American College of Cardiology, 2005
  • Fellow, Royal College of Physicians, UK, 2004
  • Fellow, Academy of Medicine, 2003
  • Member, Royal College of Physicians (UK), 1995
  • First Joint Ministry of Health-Health Science Authority (MOH-HAS) Cell, Tissue, Gene Therapy Services and Products Working Committee Meeting
  • Associate Professor, Duke-NUS Medical School
  • Adjunct Professor, Nanyang Technology University Singapore

Awards

  • Nominated Singapore Cardiac Society Lecturer, 2011
  • Group CEO (SingHealth) Excellence Award (Biomedical Research), 2008
  • Service Quality Award (Gold) National Heart Centre Singapore, 2008
  • Group CEO (Singhealth) Excellence Award Nominee (Open Cat: Research), 2007
  • Service Quality Award (Silver) National Heart Centre Singapore, 2006
  • Service Quality Award (Silver) National Heart Centre Singapore, 2005
  • Service Quality Award (Bronze) National Heart Centre Singapore, 2003
  • Service Quality Award (Bronze) National Heart Centre Singapore, 2002
  • Health Manpower Development Plan (HMDP) overseas fellowship (MOH): Interventional Cardiology Fellowship, Massachusetts
  • NMRC overseas research fellowship (Basic Science): Cardiovascular Research Centre, MGH/Harvard University. Bone marrow stem cell research in small animal model.
    Supervisor Dr. Mark Fishman/Dr. En Li, 2000-2001

Publications and Research Trials

  • Construction of a vascularized hydrogel for cardiac tissue formation in a porcine model. Myu Mai Ja KP, Lim KP, Chen A, Ting S, Li SQ, Tee N, Ramachandra C, Mehta A, Wong P, Oh S, Shim W. J Tissue Eng Regen Med. 2017 Dec 21. doi: 10.1002/term.2634. [Epub ahead of print]
  • Identification of a targeted and testable antiarrhythmic therapy for long-QT syndrome type 2 using a patient-specific cellular model. Mehta A, Ramachandra CJA, Singh P, Chitre A, Lua CH, Mura M, Crotti L, Wong P, Schwartz PJ, Gnecchi M, Shim W. Eur Heart J. (JIF 20.6) 2017 Jul 21. doi: 10.1093/eurheartj/ehx394
  • Fibroatheroma identification in Intravascular Optical Coherence Tomography images using deep features. Mengdi Xu, Jun Cheng, Annan Li, Lee JA, Wong DWK, Taruya A, Tanaka A, Foin N, Wong P. Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:1501-1504. doi: 10.1109/EMBC.2017.8037120.
  • Mechanical behavior of polymer-based vs. metallic-based bioresorbable stents. Ang HY, Huang YY, Lim ST, Wong P, Joner M, Foin N. J Thorac Dis. 2017 Aug;9(Suppl 9):S923-S934. doi: 10.21037/jtd.2017.06.30. Review.
  • Stent malapposition and the risk of stent thrombosis: mechanistic insights from an in vitro model. Foin N, Lu S, Ng J, Bulluck H, Hausenloy DJ, Wong PE, Virmani R, Joner M. EuroIntervention. 2017 Oct 13;13(9):e1096-e1098. doi: 10.4244/EIJ-D-17-00381. 
  • Bioresorbable stents: Current and upcoming bioresorbable technologies. Ang HY, Bulluck H, Wong P, Venkatraman SS, Huang Y, Foin N. Int J Cardiol. 2017 Feb 1;228:931-939. doi: 10.1016/j.ijcard.2016.11.258. Epub 2016 Nov 12. Review.
  • Current bioresorbable scaffold technologies for treatment of coronary artery diseases: Do polymer and Magnesium platforms differ? Foin N, Ng J, Wong P, Di Mario C. Int J Cardiol. 2016 Nov 15;223:526-528. doi: 10.1016/j.ijcard.2016.08.117. Epub 2016 Aug 7.
  • Reply: Meta-Analysis of the Index of Microvascular Resistance in Acute STEMI Using Incomplete Data. Bulluck H, Foin N, Cabrera-Fuentes HA, Yeo KK, Wong AS, Fam JM, Wong PE, Tan JW, Low AF, Hausenloy DJ. JACC Cardiovasc Interv. 2017 Feb 27;10(4):422. doi: 10.1016/j.jcin.2017.01.003. No abstract available. 
  • Index of Microvascular Resistance and Microvascular Obstruction in Patients With Acute Myocardial Infarction. Bulluck H, Foin N, Carbrera-Fuentes HA, Yeo KK, Wong AS, Fam JM, Wong P, Tan JW, Low AF, Hausenloy DJ. JACC Cardiovasc Interv. (JIF 7.42) 2016 Oct 24;9(20):2172-2174. doi: 10.1016/j.jcin.2016.08.018.
  • Bioresorbable vascular scaffold radial expansion and conformation compared to a metallic platform: insights from in vitro expansion in a coronary artery lesion model. Foin N, Lee R, Bourantas C, Mattesini A, Soh N, Lim JE, Torii R, Ng J, Liang LH, Caiazzo G, Fabris E, Kilic D, Onuma Y, Low AF, Nijjer S, Sen S, Petraco R, Al Lamee R, Davies JE, Di Mario C, Wong P, Serruys PW. EuroIntervention.(JIF 3.86) 2016 Sep 18;12(7):834-44. doi: 10.4244/EIJV12I7A138.
  • Angiographic, optical coherence tomography and histology findings from combination of a drugcoated balloon with an everolimus-eluting stent in a porcine model. Ong PJ, Kubo T, Watson TJ, Seah AS, Wong P, Akasaka T. Int J Cardiol. (JIF 4.09) 2016 Nov 15;223:665-668. doi: 10.1016/j.ijcard.2016.08.268.
  • Early coverage of drug-eluting stents analysed by optical coherence tomography: evidence of the impact of stent apposition and strut characteristics on the neointimal healing process. Lee R, Foin N, Ng J, Allen J, Soh N, Ang I, Shim W, Torii R, Wong P. EuroIntervention.(JIF 3.86) 2016 Aug 5;12(5):e605-14. doi: 10.4244/EIJV12I5A100. 
  • Bioresorbable Scaffold Thrombosis: Why BRS Size Matters. Foin N, Mattesini A, Wong P, Di Mario C. J Am Coll Cardiol.(JIF 17.7) 2016 Aug 2;68(5):571-2. doi: 10.1016/j.jacc.2016.03.603. 
  • Over-expansion capacity and stent design model: An update with contemporary DES platforms. Ng J, Foin N, Ang HY, Fam JM, Sen S, Nijjer S, Petraco R, Di Mario C, Davies J, Wong P. Int J Cardiol. (JIF 4.09) 2016 Oct 15;221:171-9. doi: 10.1016/j.ijcard.2016.06.097. 
  • Optimization of coronary optical coherence tomography imaging using the attenuation-compensated technique: a validation study. Teo JC, Foin N, Otsuka F, Bulluck H, Fam JM, Wong P, Low FH, Leo HL, Mari JM, Joner M, Girard MJ, Virmani R. Eur Heart J Cardiovasc Imaging. (JIF 3.669) 2016 Jul 28. pii: jew153. [Epub ahead of print]
  • ErbB4 Activated p38γ MAPK Isoform Mediates Early Cardiogenesis Through NKx2.5 in Human Pluripotent Stem Cells. Ramachandra CJ, Mehta A, Wong P, Shim W. Stem Cells. 2015 (JIF 6.17) Sep 29. doi: 10.1002/stem.2223. [Epub ahead of print] 16. Very late metallic stent malapposition and in-stent restenosis treated with a bioresorbable scaffold: a novel alternative for an old problem. Foin N, Lee R, Wong P, Low AF. EuroIntervention. (JIF 3.86) 2015 Aug 22;11(4):e1. doi: 10.4244/EIJV11I4A88 
  • Bioabsorbable vascular scaffold overexpansion: insights from in vitro post-expansion experiments. Foin N, Lee R, Mattesini A, Caiazzo G, Fabris E, Kilic D, Chan JN, Huang Y, Venkatraman SS, Di Mario C, Wong P, Nef H. EuroIntervention. .(JIF 3.86) 2015 Jul 8;11(3). pii: 20141213-04. doi: 10.4244/EIJY15M07_02
  • Molecular pathogenesis of Marfan syndrome. Ramachandra CJ, Mehta A, Guo KW, Wong P, Tan JL, Shim W. Int J Cardiol. (JIF 4.09) 2015 May 6;187:585-591. doi: 10.1016/j.ijcard.2015.03.423. Epub 2015 Mar 31.
  • Electrotonic coupled metabolic purification of chick cardiomyocytes. Shim W, Yu H, Ja KP, Parasuram M, Lim KP, Wong P. Methods Mol Biol. 2015;1299:167-75. doi: 10.1007/978-1-4939-2572-8_14. 
  • Intravascular Assessment of Arterial Disease Using Compensated OCT in Comparison With Histology. Lee R, Foin N, Otsuka F, Wong P, Mari JM, Joner M, Girard MJ, Virmani R. JACC Cardiovasc Imaging. (7.81) 2015 Mar 12. pii: S1936-878X(15)00035-2. doi: 10.1016/j.jcmg.2015.01.012.
  • Evaluation of the cardiotoxicity of mitragynine and its analogues using human induced pluripotent stem cell-derived cardiomyocytes. Lu J, Wei H, Wu J, Jamil MF, Tan ML, Adenan M, Wong P, Shim W. PLoS One. (JIF 3.06) 2014 Dec 23;9(12):e115648. doi: 10.1371/journal.pone.0115648 eCollection 2014.
  • Impact of stent strut design in metallic stents and biodegradable scaffolds. Foin N, Lee RD, Torii R, Guitierrez-Chico JL, Mattesini A, Nijjer S, Sen S, Petraco R, Davies JE, Di Mario C, Joner M, Virmani R, Wong P. Int J Cardiol. (JIF 4.09) 2014 Oct 7;177(3):800-808. doi: 10.1016/j.ijcard.2014.09.143.
  • Biodegradable vascular scaffold: is optimal expansion the key to minimising flow disturbances and risk of adverse events? Foin N, Torii R, Mattesini A, Wong P, Di Mario C. EuroIntervention.(JIF 3.86) 2014 Nov 25. pii: 20141108e. doi: 10.4244/EIJY14M11_09.
  • Tumor necrosis factor-α-induced nuclear factor-kappaB activation in human cardiomyocytes is mediated by NADPH oxidase. Moe KT, Khairunnisa K, Yin NO, Chin-Dusting J, Wong P, Wong MC. J Physiol Biochem. 2014 Sep;70(3):769-79. doi: 10.1007/s13105-014-0345-0. Epub 2014 Jul 25
  • iPSC-derived human mesenchymal stem cells improve myocardial strain of infarcted myocardium. Miao Q, Shim W, Tee N, Lim SY, Chung YY, Ja KP, Ooi TH, Tan G, Kong G, Wei H, Lim CH, Sin YK, Wong P. J Cell Mol Med. 2014 Aug;18(8):1644-54. doi: 10.1111/jcmm.12351. Epub 2014 Jun 28 
  • Modifying effect of dual antiplatelet therapy on incidence of stent thrombosis according to implanted drug-eluting stent type. Camenzind E, Boersma E, Wijns W, Mauri L, Rademaker-Havinga T, Ordoubadi FF, Suttorp MJ, Al Kurdi M, Steg PG; PROTECT Steering Committee and Investigators. Collaborators (239) Wong P. Eur Heart J. (JIF 15.2) 2014 Aug 1;35(29):1932-48. doi: 10.1093/eurheartj/ehu084. Epub 2014 Mar 13.
  • Incomplete Stent Apposition Causes High Shear Flow Disturbances and Delay in Neointimal Coverage as a Function of Strut to Wall Detachment Distance: Implications for the Management of Incomplete Stent Apposition. Foin N, Gutiérrez-Chico JL, Nakatani S, Torii R, Bourantas CV, Sen S, Nijjer S, Petraco R, Kousera C, Ghione M, Onuma Y, Garcia-Garcia HM, Francis DP, Wong P, Di Mario C, Davies JE, Serruys PW. Circ Cardiovasc Interv. (JIF 5.7) 2014 Mar 18. [Epub ahead of print] 
  • Re-trafficking of HERG Reverses Long QT Syndrome 2 Phenotype in Human iPS-derived Cardiomyocytes. Mehta A, Sequiera GL, Ramachandra CJ, Sudibyo Y, Chung Y, Jingwei S, Wong KY, Tan TH, Wong P, Liew R, Shim W. Cardiovasc Res. (JIF 5.46) 2014 Mar 12. [Epub ahead of print] 
  • Electrophysiology of human cardiac atrial and ventricular telocytes. Sheng J, Shim W, Lu J, Lim SY, Ong BH, Lim TS, Liew R, Chua YL, Wong P. J Cell Mol Med. (JIF 4.94) 2014 Feb;18(2):355-62. doi: 10.1111/jcmm.12240.
  • Hydrogen sulphide suppresses human atrial fibroblast proliferation and transformation to myofibroblasts. Sheng J, Shim W, Wei H, Lim SY, Liew R, Lim TS, Ong BH, Chua YL, Wong P. J Cell Mol Med. (JIF 4.94) 2013 Oct;17(10):1345-54. doi: 10.1111/jcmm.12114. Epub 2013 Aug 15. 
  • Modeling type 3 long QT syndrome with cardiomyocytes derived from patient-specific induced pluripotent stem cells. Ma D, Wei H, Zhao Y, Lu J, Li G, Sahib NB, Tan TH, Wong KY, Shim W, Wong P, Cook SA, Liew R. Research and Development Unit (RDU), National Heart Centre Singapore, Singapore. Int J Cardiol. 2013 Aug 15. pii: S0167-5273(13)01540-4. doi: 10.1016/j.ijcard.2013.08.015 
  • Preliminary experience with a novel TITAN-V stent for ostial coronary lesions in an experimental animal model. Ong PJ, Khurana R, Hou PW, Lukito AA, Ho HH. Int J Cardiol. 2013 Jul 1;166(3):e53-5. doi: 10.1016/j.ijcard.2013.01.172. Epub 2013 Mar 7. 
  • Tumor Necrosis Factor-α Induces Aortic Intima-Media Thickening via Perivascular Adipose Tissue Inflammation. Moe KT, Naylynn TM, Yin NO, Khairunnisa K, Allen JC, Wong MC, Chin-Dusting J, Wong P. J Vasc Res. 2013 May 22;50(3):228-237. [Epub ahead of print]
  • Critical path in cardiac stem cell therapy: an update on cell delivery. Shim W, Mehta A, Wong P, Chua T, Koh TH. Cytotherapy. 2013 Apr;15(4):399-415. doi: 10.1016/j.jcyt.2012.11.003. Epub 2013 Jan 5. 
  • Identification and characterization of calcium sparks in cardiomyocytes derived from human induced pluripotent stem cells. Zhang GQ, Wei H, Lu J, Wong P, Shim W. PLoS One. 2013;8(2):e55266. doi: 10.1371/journal.pone.0055266. Epub 2013 Feb 7. 
  • Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy. (Journal Impact Factor : 14.1) Ma D, Wei H, Lu J, Ho S, Zhang G, Sun X, Oh Y, Tan SH, Ng ML, Shim W, Wong P, Liew R. Eur Heart J. 2013 Apr;34(15):1122-33. doi: 10.1093/eurheartj/ehs226. Epub 2012 Jul 13. 
  • Pharmacoelectrophysiology of viral-free induced pluripotent stem cell-derived human cardiomyocytes. Mehta A, Chung Y, Sequiera GL, Wong P, Liew R, Shim W. Toxicol Sci. 2013 Feb;131(2):458-69. doi: 10.1093/toxsci/kfs309. Epub 2012 Oct 22. 
  • Hydrogen sulfide suppresses outward rectifier potassium currents in human pluripotent stem cellderived cardiomyocytes. Wei H, Zhang G, Qiu S, Lu J, Sheng J, Manasi, Tan G, Wong P, Gan SU, Shim W. PLoS One. 2012;7(11):e50641. doi: 10.1371/journal.pone.0050641. Epub 2012 Nov 30. 
  • Stent thrombosis and major clinical events at 3 years after zotarolimus-eluting or sirolimus-eluting coronary stent implantation: a randomised, multicentre, open-label, controlled trial. Camenzind E, Wijns W, Mauri L, Kurowski V, Parikh K, Gao R, Bode C, Greenwood JP, Boersma E, Vranckx P, McFadden E, Serruys PW, O'Neil WW, Jorissen B, Van Leeuwen F, Steg PG; PROTECT Steering Committee and Investigators ( Wong P ). Lancet. 2012 Oct 20;380(9851):1396-405. doi: 10.1016/S0140-6736(12)61336-1. Epub 2012 Aug 27.
  • Hemodynamic Contribution of Stem Cell Scaffolding in Acute Injured Myocardium. Qian L, Shim W, Gu Y, Shirhan M, Lim KP, Tan LP, Lim CH, Sin YK, Wong P. Tissue Eng Part A. 2012 May 18. [Epub ahead of print].
  • One-step derivation of cardiomyocytes and mesenchymal stem cells from human pluripotent stem cells. Wei H, Tan G, Manasi, Qiu S, Kong G, Yong P, Koh C, Ooi TH, Lim SY, Wong P, Gan SU, Shim W. Stem Cell Res. 2012 Apr 24;9(2):87-100. [Epub ahead of print] 
  • Pharmacological response of human cardiomyocytes derived from virus-free induced pluripotent stem cells. Mehta A, Chung YY, Ng A, Iskandar F, Atan S, Wei H, Dusting G, Sun W, Wong P, Shim W. Cardiovasc Res. 2011 Sep 1;91(4):577-86. Epub 2011 May 12. 
  • Comparison of novel 6.5 Fr sheathless guiding catheters versus 5 Fr guiding catheters for transradial coronary intervention. Chiam PT, Liu B, Wong AS, Wong P, Lim ST, Koh TH, Lim VY. EuroIntervention. 2011 Dec 13;7(8):930-5. Wei H 
  • G-CSF administration in acute myocardial infarction: what is the best timing? Reply. Shim W, Mehta A, Lim CH, Chua T, Wong P. Cardiovasc Res. 2011 Apr 19. [Epub ahead of print] No abstract available.
  • Nox2 and Nox4 mediate tumor necrosis factor-alpha-induced ventricular remodeling in mice. Moe KT, Yin NO, Naylynn TM, Khairunnisa K, Wutyi MA, Gu Y, Atan MS, Wong MC, Koh TH, Wong P. J Cell Mol Med. 2011 Jan 20. doi: 10.1111/j.1582-4934.2011.01261.x. [Epub ahead of print]
  • G-CSF for stem cell therapy in acute myocardial infarction: friend or foe? Shim W, Mehta A, Lim SY, Zhang G, Lim CH, Chua T, Wong P. Cardiovasc Res. 2010 Oct 25. [Epub ahead of print] 
  • Different expression of large-conductance calcium-activated K+ channels in human internal mammary and radial arteries. Shao Y, Liew R, Guan B, Wong P, Shim WS, Chua Y, He G. Cardiovasc Res. 2010 Oct 25. [Epub ahead of print]
  • Dose-dependent systolic contribution of differentiated stem cells in post-infarct ventricular function. Shim WS, Tan G, Gu Y, Qian L, Li S, Chung YY, Lim SY, Sim E, Chuah SC, Wong P. J Heart Lung Transplant. 2010 Aug 3. [Epub ahead of print]
  • Differential effect of myocardial matrix and integrins on cardiac differentiation of human mesenchymal stem cells. Tan G, Shim W, Gu Y, Qian L, Chung YY, Lim SY, Yong P, Sim E, Wong P. Differentiation. 2010 Apr-Jun;79(4-5):260-71. Epub 2010 Mar 21. 
  • Acute coronary syndrome: from epidemiology to treatment. Lee CH, Wong P. (Guest Editor) Ann Acad Med Singapore. 2010 Mar;39(3):161-2. 
  • Complete atrioventricular block complicating acute anterior myocardial infarction can be reversed with acute coronary angioplasty. Ho KW, Koh TH, Wong P, Wong SL, Lim YT, Lim ST, Hsu LF. Ann Acad Med Singapore. 2010 Mar;39(3):254-7. 
  • Current trends in diagnostic biomarkers of acute coronary syndrome. Moe KT, Wong P. Ann Acad Med Singapore. 2010 Mar;39(3):210-5.
  • Rationale and design of the Patient Related OuTcomes with Endeavor versus Cypher stenting Trial (PROTECT): randomized controlled trial comparing the incidence of stent thrombosis and clinical events after  sirolimus or zotarolimus drug-eluting stent implantation. Camenzind E, Wijns W, Mauri L, Boersma E, Parikh K, Kurowski V, Gao R, Bode C, Greenwood JP, Gershlick A, O'Neill W, Serruys PW, Jorissen B, Steg PG; PROTECT Steering Committee and Investigators. Collaborators (216) Wong P Am Heart J. 2009 Dec;158(6):902-909.e5.
  • Label-free impedance detection of low levels of circulating endothelial progenitor cells for point-of-care diagnosis. Ng SY, Reboud J, Wang KY, Tang KC, Zhang L, Wong P, Moe KT, Shim W, Chen Y. Biosens Bioelectron. 2009 Oct 1. [Epub ahead of print] 
  • Human bone marrow-derived adult stem cells for post-myocardial infarction cardiac repair: current status and future directions. Wei HM, Wong P, Hsu LF, Shim W. Singapore Med J. 2009 Oct;50(10):935-42.
  • Cell delivery and tracking in post-myocardial infarction cardiac stem cell therapy: an introduction for clnical researchers. Wei H, Ooi TH, Tan G, Lim SY, Qian L, Wong P, Shim W. Heart Fail Rev. 2009 Jan;15(1):1-14. [Epub ahead of print]
  • Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population. Moe KT, Woon FP, De Silva DA, Wong P, Koh TH, Kingwell B, Chin-Dusting J, Wong MC. Eur J Neurology 2008 Dec; 15(12):1309-14 
  • Myoblast transplantation for cardiac repair: from automyoblast to allomyoblast transplantation. Guo C, Haider HKh, Wang C, Tan RS, Shim WS, Wong P, Sim EK. Ann Thorac Surg. 2008 Dec;86(6):1841-8.
  • Structural stability of neoangiogenic intramyocardial microvessels supports functional recovery in chronic ischemic myocardium. Winston S.N. Shim, Sze Yun Lim, Shi Qi Li, yacui Gu, Hwee Choo Ong, In Chin Song, Seng Chye Chuah, Philip Wong. J Mol Cell Cardiol 2008 Jul; 45(1):70-80. Epub 2008 Apr 27
  • Angiopoietin: A Tie(d) Balance in Tumor Angiogenesis. Winston Shim, Ivy Ho and Philip Wong. Mol Cancer Res. 2007 Jul;5(7):655-65 
  • Clinical features and outcome of emergency percutaneous intervention of left main coronary artery occlusion in acute myocardial infarction. Tang HC, Wong A, Wong P, Chua TS, Koh TH, Lim ST. Singapore Med J 2007; 48(12):1122. 
  • Myoblast-based cardiac repair: xenomyoblast versus allomyoblast transplantation. Guo C, Haider HKh, Shim WS, Tan RS, Ye L, Jiang S, Law PK, Wong P, Sim EK. J Thorac Cardiovasc Surg. 2007 Nov;134(5):1332-9. 
  • Association analysis of endothelial nitric oxide synthase gene polymorphism with primary hypertension in a Singapore population. Moe KT, Lim ST, Wong P, Chua T, Desilva DA, Koh TH, Wong MC, Chin-Dusting J. J Hum Hypertens. 2006 Oct 5; [Epub ahead of print] 
  • Angiopoietin-1 promotes functional neovascularization that relieves ischemia by improving regional reperfusion in a swine chronic myocardial ischemia model. Winston S. N. Shim, Wei Li, Li Zhang, Shiqi Li, Hwee Choo Ong, In-Chin Song, Akanksha Bapna, Ruowen Ge, Yean Teng Lim, Seng Chye Chuah, Eugene K. W. Sim, Philip Wong. J Biomed Sci. 2006 Mar 18; [Epub ahead of print] 
  • Ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte-like cells. Shim W, Shujia Jiang, Wong P, Tan J, Chua YL, Tan YS, Yoong KS, Chong HL, Chua T, Teh Ming, Liu TC, Sim EK. (Top 10 downloaded article from this journal for year 2004) Biochem Biophys Res Commun. 2004 Nov 12;324(2):481-8
  • Angiomyogenesis for cardiac repair using human myoblasts as carriers of human vascular endothelial growth factor. Kh Haider H, Ye L, Jiang S, Ge R, Law PK, Chua T, Wong P, Sim EK. J Mol Med. 2004 Jun 3 [Epub ahead of print] 
  • Combined Fibrinolysis using Reduced dose Alteplase plus abciximab with immediate rescue angioplasty versus primary angioplasty with adjunct use of abciximab for the treatment of acute myocardial infarction. Asia Pacific Acute Myocardial Infarction Trial (APAMIT) Pilot Study. Wong A, Mak KH, Chan C, Koh TH, Lau KW, Lim TT, Lim ST, Wong P, Sim LL, Lim YT, Tan HC, Lim YL.Catheter Cardiovasc Interv. 2004 Aug;62(4):445-52
  • Cellular Cardiomyoplasty: State of the Art. Shim W, Wong P. Ann Acad Med Singapore 2004;33:451-60
  • The Effect of Glycoprotein IIb/IIIa Receptor Inhibitor on the Microcirculation in Patients Undergoing High-Risk Coronary Stenting; A Prospective, Randomized study. Philip Wong, Scott Harding, Ignacio, Inglessis, C. Joon Choi, Darren Walters, Yuchiao Chang,.Giogio Gimelli, Ik-Kyung Jang. J Thromb Thrombolysis. 2003 Dec;16(3):163-6 
  • Acute coronary syndrome is a common clinical presentation of in-stent restenosis. Walters DL, Harding SA, Walsh CR, Wong P, Pomerantsev E, Jang IK. Am J Cardiol 2002 Mar 1;89(5):491-4. 
  • Vascular Complications after Hemostatic Puncture Closure Device is not higher in Overweight patients. Wong P, Harding S, Oesterle SN, Hull M, Jang IK. J Invasive Cardiol 2001 Sep;13(9):623-5.
  • Stenting in Non-Stress/Benestent lesions. Wong P, KW Lau, YL Lim, SN Oesterle. Catheter Cardiovasc Interv 2000 Oct;51(2):223-33.

Case Reports
  • Coronary subclavian steal syndrome: a rare cause of acute myocardial infarction. Tan JW, Johan BA, Cheah FK, Wong P. Singapore Med J. 2007 Jan;48(1):e5-8. 
  • Electrocardiographical case. An elderly lady with chest pain. Isolated posterior myocardial infarct (MI). Chiam P, Chuah SC, Wong P, Teo WS. Singapore Med J. 2006 Feb;47(2):166-9. 
  • Spontaneous spiral dissection of a LIMA-LAD graft. Wong P, Rubinstein M, Inglessis I, Ferrell M, Leinbach R. J Interv Cardiol. 2004 Aug;17(4):211-213
Book Chapters
  • Coronary Stents. Briain D. Macneill, Ik-Kyung Jang and Philip Wong. Chapter 15-1: Becker/Harrington- CLINICAL, INTERVENTIONAL AND INVESTIGATIONAL THROMBOCARDIOLOGY 2005
  • Arteriotomy Closure Devices: To use or not to use? Wong P. 11th Singapore LIVE course book 2002
  • Current Strategies in Treating Long Diffuse Coronary Lesions. Chan C, Wong P, Mak K.H, Ho S.W., Ormiston J, Y.L. Lim. Paris Course on Revascularization course book 2002
  • Percutaneous Coronary Intervention of Diffuse Coronary Artery Disease: An end to a ‘long’ problem? Wong P, Manallo C, Lingamanaiker J, Ormiston J, Chan C. Paris Course on Revascularization course book 2003

Research Trials

  • SingXpand “SINGaporean Program performed with an eXPANsion medical Device” Singapore pilot study evaluating the safety and the efficacy of the intramyocardial injection of expanded CD34+ stem cells (ProtheraCytes®) in the treatment of patients with De Novo Acute Myocardial Infarction (Current PI)