Otherwise instructed by the doctor, Vagifem is usually administered vaginally 1 tablet daily for 2 weeks, followed by 1 tablet twice a week.

The Vagifem vaginal tablet is to be placed into your vagina with the help of the applicator.

​	​ Tear off one single blister pack and open at the push button end of the pack by pressing. The tablet is at the other end of the applicator. Do not get the tablet wet.
​	​ Standing on one foot on a chair or lying on your back, insert the applicator, with tablet at the end, into the vagina as far as it will comfortably go. During insertion, take care not to push the button at the end until the applicator is fully inserted.
​	​ When the applicator is fully inserted, press the push button at the end of the applicator until a click is felt. This indicates that the tablet has been released from the end of applicator. The tablet will stick to vaginal wall.
​	​ Withdraw and throw away the applicator. After insertion, try to remain in a lying position for at least 30 minutes to prevent the tablet from falling out from the vagina.

Skip the missed dose and go back to your usual timing of administration the next day. Do not use 2 doses or extra doses to make up for the missed dose.