• Drowsiness, dizziness or blurred vision. Do not drive, operate machinery, or perform anything that requires mental alertness if you have these symptoms. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially for elderly patients.
• ​Dry eyes. Use normal saline eye drops to relieve eye dryness.
• Dry mouth. Chewing sugarless gum or sucking hard candy or ice will help. Saliva substitute can also be applied to relieve dry mouth.
• Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help.​​

Other common side effects that usually do not required medical attention include headache, dry skin, and nausea. Report these to your doctor if they persist and are bothersome. 

Imipramine can affect blood glucose (sugar) levels. If you are a diabetic, check your blood sugar more often than usual, especially during the first few weeks of imipramine treatment. Call your doctor if you notice a change in the results of blood or urine glucose tests.

Mirabegron can affect blood pressure. If you have high blood pressure, check your blood pressure more often than usual, especially during the first few weeks of mirabegron treatment. Inform your doctor if you notice an increasing trend of blood pressure readings or when your blood pressure is at 160/90mmHg. You have to stop mirabegron treatment immediately if your blood pressure is at 180/110mmHg and seek immediate medical attention.